Year 2020, Volume 4 , Issue 8, Pages 664 - 668 2020-08-01

Polikistikover sendromlu hastalarda visseral adiposite indeksi ve lipid birikim ürünlerinin metabolik, antropometrik ve hormonal parametrelerle ilişkisi
The relation of visceral adiposity index and lipid accumulation product with metabolic, anthropometric, and hormonal parameters in patients with polycystic ovary syndrome

Gültekin ADANAS [1] , Gülten ÖZGEN [2]


Amaç: Polikistik over sendromu (PKOS) üreme çağında en sık görülen endokrinopati olup santral obezite, glukoz intoleransı, dislipidemi ve hipertansiyon ile ilişkilidir. Visseral adipozite indeksi (VAI) ve lipid birikim ürünleri (LAP) insülin duyarlılığı dışında kardiyovasküler ve serebrovasküler olaylar ile de ilişkili olduğu saptanmıştır. Bizler de, bu çalışmamızda PKOS ve kontrol grubu hastalarımızda VAI ve LAP ile metabolik, antropometrik ve hormonal parametreler arasındaki ilişkileri değerlendirdik. Yöntemler: Çalışmaya 18-35 yaş aralığında 106’sı Rotterdam kriterlerine göre PKOS grubunda olmak üzere toplam 172 hasta dahil edildi. Diabetes mellitus, Cushing sendromu, hiperprolaktinemi, konjenital adrenal hiperplazi, hipertansiyon ve tiroid bozukluğu olan hastalar çalışmaya dahil edilmedi. LAP ve VAI indekslerinin hesaplanması için HDL ve trigliserid düzeylerine bakıldı. Bulgular: PKOS’lu hasta grubunda LAP ile HDL-C (r=-0,644) arasında anlamlı negatif korelasyon saptanırken, trigliserid (r=0,706) ve kalça çevresi (r=0,872) arasında pozitif korelasyon saptandı. Yine VAI ile bel çevresi (r=0,625) ve HOMA-IR (r=0,462) arasında pozitif korelasyon saptandı. Sonuç: Bu çalışmada PKOS hasta grubunda VAI’nın insülin direncini belirlemede yararlı bir indeks olduğu sonucuna varıldı.
Aim: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age and is associated with glucose intolerance, central obesity, hypertension, and dyslipidemia. The Visceral Adiposity Index (VAI) and Lipid Accumulation Product (LAP) are effective indices for predicting insulin resistance are associated with cardiovascular and cerebrovascular events. In this study, we aimed to investigate the relationship of VAI and LAP with metabolic, anthropometric, and hormonal parameters in PCOS patients. Methods: A total of 106 patients with PCOS who were diagnosed according to the Rotterdam criteria and 66 healthy controls without PCOS aged 18-35 years were included in this prospective, case-control study. Patients with diabetes mellitus, Cushing syndrome, hyperprolactinemia, congenital adrenal hyperplasia, hypertension, or thyroid disorder were excluded. The VAI and LAP were calculated based on the high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) levels. Results: There was a negative, significant correlation between LAP and HDL-C (r=-0.644), a positive, significant correlation between TG (r=0.706) and hip circumference (r=0.872), and a positive, significant correlation between VAI and waist circumference (r=0.625) in the PCOS group. There was also a positive, significant correlation between HOMA-IR and VAI in the PCOS group (r=0.462). Conclusion: Our study results suggest that VAI seems to be a more useful index for predicting insulin resistance in PCOS patients.
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Primary Language en
Subjects Obstetrics and Gynecology
Journal Section Research article
Authors

Orcid: 0000-0002-9113-9846
Author: Gültekin ADANAS (Primary Author)
Institution: BURSA YÜKSEK İHTİSAS EĞİTİM VE ARAŞTIRMA HASTANESİ, KADIN HASTALIKLARI VE DOĞUM
Country: Turkey


Orcid: 0000-0002-7888-7583
Author: Gülten ÖZGEN
Institution: BURSA YÜKSEK İHTİSAS EĞİTİM VE ARAŞTIRMA HASTANESİ, KADIN HASTALIKLARI VE DOĞUM
Country: Turkey


Dates

Publication Date : August 1, 2020

Bibtex @research article { josam755729, journal = {Journal of Surgery and Medicine}, issn = {}, eissn = {2602-2079}, address = {jsurgmed@gmail.com}, publisher = {Fatih BAŞAK}, year = {2020}, volume = {4}, pages = {664 - 668}, doi = {10.28982/josam.755729}, title = {The relation of visceral adiposity index and lipid accumulation product with metabolic, anthropometric, and hormonal parameters in patients with polycystic ovary syndrome}, key = {cite}, author = {Adanas, Gültekin and Özgen, Gülten} }
APA Adanas, G , Özgen, G . (2020). The relation of visceral adiposity index and lipid accumulation product with metabolic, anthropometric, and hormonal parameters in patients with polycystic ovary syndrome . Journal of Surgery and Medicine , 4 (8) , 664-668 . DOI: 10.28982/josam.755729
MLA Adanas, G , Özgen, G . "The relation of visceral adiposity index and lipid accumulation product with metabolic, anthropometric, and hormonal parameters in patients with polycystic ovary syndrome" . Journal of Surgery and Medicine 4 (2020 ): 664-668 <http://jsurgmed.com/en/pub/issue/56401/755729>
Chicago Adanas, G , Özgen, G . "The relation of visceral adiposity index and lipid accumulation product with metabolic, anthropometric, and hormonal parameters in patients with polycystic ovary syndrome". Journal of Surgery and Medicine 4 (2020 ): 664-668
RIS TY - JOUR T1 - The relation of visceral adiposity index and lipid accumulation product with metabolic, anthropometric, and hormonal parameters in patients with polycystic ovary syndrome AU - Gültekin Adanas , Gülten Özgen Y1 - 2020 PY - 2020 N1 - doi: 10.28982/josam.755729 DO - 10.28982/josam.755729 T2 - Journal of Surgery and Medicine JF - Journal JO - JOR SP - 664 EP - 668 VL - 4 IS - 8 SN - -2602-2079 M3 - doi: 10.28982/josam.755729 UR - https://doi.org/10.28982/josam.755729 Y2 - 2020 ER -
EndNote %0 Journal of Surgery and Medicine The relation of visceral adiposity index and lipid accumulation product with metabolic, anthropometric, and hormonal parameters in patients with polycystic ovary syndrome %A Gültekin Adanas , Gülten Özgen %T The relation of visceral adiposity index and lipid accumulation product with metabolic, anthropometric, and hormonal parameters in patients with polycystic ovary syndrome %D 2020 %J Journal of Surgery and Medicine %P -2602-2079 %V 4 %N 8 %R doi: 10.28982/josam.755729 %U 10.28982/josam.755729
ISNAD Adanas, Gültekin , Özgen, Gülten . "The relation of visceral adiposity index and lipid accumulation product with metabolic, anthropometric, and hormonal parameters in patients with polycystic ovary syndrome". Journal of Surgery and Medicine 4 / 8 (August 2020): 664-668 . https://doi.org/10.28982/josam.755729
AMA Adanas G , Özgen G . The relation of visceral adiposity index and lipid accumulation product with metabolic, anthropometric, and hormonal parameters in patients with polycystic ovary syndrome. J Surg Med. 2020; 4(8): 664-668.
Vancouver Adanas G , Özgen G . The relation of visceral adiposity index and lipid accumulation product with metabolic, anthropometric, and hormonal parameters in patients with polycystic ovary syndrome. Journal of Surgery and Medicine. 2020; 4(8): 664-668.