Year 2018, Volume 2 , Issue 3, Pages 273 - 277 2018-09-01

Postmenapozal kadınlarda koklear fonksiyona osteoporozun etkisi: Gözlemsel bir çalışma
The effect of osteoporosis on cochlear function in postmenopausal women: An observational study

Saime SAĞIROĞLU [1] , Tuba Tülay KOCA [2]


Amaç: İşitme kaybı ve osteoporoz sık görülen geriatrik sendromlardandır. Az sayıda klinik çalışmada osteoporozun koklear fonksiyona etkisi olabileceği yönünde delil bulunmuştur. Burada osteoporoz hastalarında kohlear fonksiyon, otoaküstik emisyon test (OAET) ölçümleri ile değerlendirildi. 

Yöntemler: Çalışma kesitsel gözlemsel olarak diüzenlendi. Çalışmaya 40-75 yaş aralığında postmenapozal dönemde 50 kadın hasta dahil edildi. Tüm hastalarda yaş, vücut kitle indeksi (BMI), vitamin D düzeyi kayıt edildi. Hava ve kemik iletimli işitme hassasiyetini ölçmek için odiyometrik eşik testi kullanıldı. Kalça ve omurganın kemik mineral yoğunluğu (BMD) dual enerji X-ışını absorpsiyometri (DEXA) kullanılarak ölçüldü. Vertebra L1-4 t skor<-2,5 osteoporoz, -2,5 ila -1 arası osteopenik olarak grup ikiye ayrıldı ve tüm parametreler karşılaştırıldı. Geçici olarak uyarılmış (TE) ve distorsiyon ürünü (DP) otoakustik emisyonları kaydedildi.

Bulgular: Tüm grup yaş ortalaması 58,6±7,9 yıl idi. Buna göre TE left 0.75 Hz’de osteopenik grupta daha yüksek frekansda anlamlı farklı idi (p=0,015). İşitme testlerinde sadece her iki kulak 6.000 db’de osteopenik grup daha yüksek frekansda anlamlı farklı idi (p=0,049 / p=0,016).

Femur t skor<-1,0 göre grup ikiye ayrıldığında TEright_2.5 (p=0,015), TEright_3.5 (p=0,04), TEright_overall (p=0,030), TEleft_1.7.5 (p=0,043), TEleft_overall (p=0,046), DPright_1 (p=0.049), DPleft_6 (p=0,039) osteoporotik grupta daha yüksek frekanslarda sonuçlar olduğu gözlendi. Lomber t skor BMI ile pozitif korele (p=0,042/r=0,288) idi. Osteoporotik grubda BMI daha düşük idi. Hastaların tamamında timpanogram sonuçları Tip A idi. TE pozitiflik oranı (S/N>3) %60,8, DP pozitiflik oranı (S/N>3) %39,2 idi. 

Sonuç: Kalça BMD skorlarına göre, osteopenik_osteoporotik grup (T skor<-1) hem koklear hem da işitme testlerinde normal kişilere göre yüksek frekanslar gösterdiler. Osteoporotik grupta hem OAET sonuçları hemde odiyolojik verilerin daha yüksek frekanslarda olması osteoporozun koklear ve işitme fonksiyonuna olumsuz etkisini desteklemektedir.  İşitme kaybı olan bireyler osteoporoz yönünden taranmalıdır.


Aim: Hearing loss and osteoporosis are common geriatric syndromes. Evidence suggests that osteoporosis may have an effect on cochlear function in a small number of clinical trials. Here, cochlear function in osteoporosis patients was assessed by otoacoustic emission test measurements.

Methods: The study designed as cross-sectional and observational. Forty female patients were included in the postmenopausal period at the age of 40-75 years. Age, body mass index (BMI), vitamin D level were recorded in all patients. Audiometric threshold testing was used to measure air- and bone-conduction hearing sensitivity. Bone mineral density (BMD) of the hip and vertebra was measured using dual-energy X-ray absorptiometry (DEXA). According to vertebra L1-4 t score <-2.5 osteoporosis, -2.5 to -1 osteopenic, the group divided into two and all parameters were compared. Transiently evoked (TE), and distortion-product (DP) otoacoustic emissions were recorded.

Results: The mean age of the whole group was 58.6 ± 7.9 years. Accordingly, TE left was significantly different in the higher frequency in the osteopenic group at 0.75 Hz (p = 0.015). In audiometric tests, only the osteopenic group at 6,000 dB was significantly different in the higher frequency of both ears (p = 0.049 / p = 0.016).

When the group divided into two according to femur t score <-1.0; TEright_3.5 (p = 0,04), TEright_overall (p = 0,030), TEleft_1.7.5 (p = 0,043) and TEleft_overall (p = p = 0.046), DPright_1 (p = 0.049) and DPleft_6 (p = 0.039) were observed to occur at higher frequencies in the osteoporotic group. Lomber t score was positively correlated with BMI (p = 0.042 / r = 0.288). BMI was lower in the osteoporotic group. The tympanogram results of all patients were Type A. The TE positivity rate (S / N> 3) was 60.8% and the DP positivity rate (S / N> 3) was 39.2%.

Conclusion: According to hip BMD scores, osteopenic-osteoporotic (T scor <-1) group showed higher frequencies in both cochlear and hearing tests than normal subjects. The high frequencies in both OAET results and odiologic data in osteoporotic group support the adverse effect of osteoporosis on cochlear and hearing function. Individuals with hearing loss should be screened for osteoporosis.


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Primary Language en
Subjects Medicine
Journal Section Research article
Authors

Orcid: 0000-0003-2608-7274
Author: Saime SAĞIROĞLU
Institution: KAHRAMANMARAŞ SÜTÇÜ İMAM ÜNİVERSİTESİ, TIP FAKÜLTESİ
Country: Turkey


Orcid: 0000-0002-4596-858X
Author: Tuba Tülay KOCA (Primary Author)
Institution: KAHRAMANMARAŞ SÜTÇÜ İMAM ÜNİVERSİTESİ, TIP FAKÜLTESİ
Country: Turkey


Dates

Publication Date : September 1, 2018

Bibtex @research article { josam429059, journal = {Journal of Surgery and Medicine}, issn = {}, eissn = {2602-2079}, address = {jsurgmed@gmail.com}, publisher = {Fatih BAŞAK}, year = {2018}, volume = {2}, pages = {273 - 277}, doi = {10.28982/josam.429059}, title = {The effect of osteoporosis on cochlear function in postmenopausal women: An observational study}, key = {cite}, author = {Sağıroğlu, Saime and Koca, Tuba Tülay} }
APA Sağıroğlu, S , Koca, T . (2018). The effect of osteoporosis on cochlear function in postmenopausal women: An observational study . Journal of Surgery and Medicine , 2 (3) , 273-277 . DOI: 10.28982/josam.429059
MLA Sağıroğlu, S , Koca, T . "The effect of osteoporosis on cochlear function in postmenopausal women: An observational study" . Journal of Surgery and Medicine 2 (2018 ): 273-277 <https://jsurgmed.com/en/pub/issue/36726/429059>
Chicago Sağıroğlu, S , Koca, T . "The effect of osteoporosis on cochlear function in postmenopausal women: An observational study". Journal of Surgery and Medicine 2 (2018 ): 273-277
RIS TY - JOUR T1 - The effect of osteoporosis on cochlear function in postmenopausal women: An observational study AU - Saime Sağıroğlu , Tuba Tülay Koca Y1 - 2018 PY - 2018 N1 - doi: 10.28982/josam.429059 DO - 10.28982/josam.429059 T2 - Journal of Surgery and Medicine JF - Journal JO - JOR SP - 273 EP - 277 VL - 2 IS - 3 SN - -2602-2079 M3 - doi: 10.28982/josam.429059 UR - https://doi.org/10.28982/josam.429059 Y2 - 2018 ER -
EndNote %0 Journal of Surgery and Medicine The effect of osteoporosis on cochlear function in postmenopausal women: An observational study %A Saime Sağıroğlu , Tuba Tülay Koca %T The effect of osteoporosis on cochlear function in postmenopausal women: An observational study %D 2018 %J Journal of Surgery and Medicine %P -2602-2079 %V 2 %N 3 %R doi: 10.28982/josam.429059 %U 10.28982/josam.429059
ISNAD Sağıroğlu, Saime , Koca, Tuba Tülay . "The effect of osteoporosis on cochlear function in postmenopausal women: An observational study". Journal of Surgery and Medicine 2 / 3 (September 2018): 273-277 . https://doi.org/10.28982/josam.429059
AMA Sağıroğlu S , Koca T . The effect of osteoporosis on cochlear function in postmenopausal women: An observational study. J Surg Med. 2018; 2(3): 273-277.
Vancouver Sağıroğlu S , Koca T . The effect of osteoporosis on cochlear function in postmenopausal women: An observational study. Journal of Surgery and Medicine. 2018; 2(3): 273-277.
IEEE S. Sağıroğlu and T. Koca , "The effect of osteoporosis on cochlear function in postmenopausal women: An observational study", Journal of Surgery and Medicine, vol. 2, no. 3, pp. 273-277, Sep. 2018, doi:10.28982/josam.429059