Year 2018, Volume 2 , Issue 3, Pages 197 - 200 2018-09-01

Frontal fibrozing alopesi'nin klinik ve demografik özelliklerinin gözden geçirilmesi
Review of clinical and demographic features of frontal fibrosing alopecia

Güldehan ATIŞ [1] , Zeynep ALTAN FERHATOĞLU [2]


Amaç: Frontal fibrozan alopesi (FFA) frontotemporal bölgede lokalize, ilerleyici bir sikatrisyel alopesidir. Etiyopatogenezi halen tam olarak bilinmemektedir. Genetik yatkınlık, hormonal ve çevresel faktörler, kişisel bakım ürünleri etyolojide suçlanmaktadır. Amacımız son 2 yıl içerisinde gözlenen FFA’lı olguların klinik ve demografik özelliklerinin incelenmesidir.

Yöntemler: Ocak 2016- Ocak 2018 tarihleri arasında dermatoloji polikliniğine FFA nedeniyle başvuran hastalar çalışmaya dahil edildi. Tanı histopatolojik olarak ya da tipik klinik bulgulara dayanılarak konuldu. Hastaların başvuru esnasındaki yaşı, hastalık başlangıç yaşı, ilişkili olabilecek tıbbi hastalıkları, aile öyküleri, menapoz durumları, klinik bulguları ve aldıkları tedaviler kaydedildi. 

Bulgular: Hastaların hepsi kadın ve postmenapozal idi. Yedi hastanın (%87,75) kaşların da dökülme mevcuttu. Yalnız saçlar hastaların beşinde (%62,5) saptandı. Frontal venlerde çökme hastaların ikisinde (%25) gözlendi. Perifoliküler eritem üç hastada (%37,5), perifoliküler skuam dört hastada (%50) gözlenirken, bebek saçı şeklinde saç çizgisi bir hastada (%12,25) gözlendi. İki hastada (%25) erken menapoz öyküsü mevcuttu. Saçların beyazlama yaş ortalaması 30.87±11.39 idi. Üç hastada (%37,5) saçlarda erken beyazlama öyküsü mevcuttu. Tüm hastalar saçlarını boyatmıştı. İlk kez saç boyatlma yaş ortalaması 31,5±10,50 idi.

Sonuç: Perifoliküler eritem ve perifoliküler skuam FFA’nın önemli trikoskopik bulgularıdır. Çevresel faktörler, otoimmün proçesler, hormonlar genetik olarak yatkın bireylerde hastalığın ortaya çıkışını kolaylaştırmaktadır. Erken saç beyazlaması ve saç boyaları (özellikle erken yaşta maruz kalmak) FFA’da tetikleyici veya etyolojik faktör olabilir.

Aim: Frontal fibrosing alopecia (FFA) is a progressive scarring alopecia that occurs on the frontotemporal area. The ethiopathogenesis of FFA is still unclear. Genetic predisposition, hormonal and environmental factors, and the use of personal care products have been put forward as etiological factors. Our aim was to evaluate the clinical and demographical features of FFA patients retrospectively during a two-year follow-up period.

Methods: Patients who admitted to our dermatology out-patient clinic between January 2016 and January 2018 were included in the study. Diagnosis was made histologically or based on the typical clinical presentation (ear to ear hair loss). Age at first presentation and onset of FFA, relevant medical comorbidities, family history, menopause status, clinical features, and medical therapies administered were recorded. 

Results: All the patients were female and post-menopausal. Seven patients (87.75%) had hair loss on the eyebrows. Lonely hairs were observed in five patients (62.5%). Depression of frontal veins was observed in two patients (25%). Perifollicular erythema was observed in three patients (37.5%), and perifollicular scale was observed in four patients (50%). One of the patients (12.25%) exhibited a doll hair line. Two patients (25%) had early menopause history. The mean age of onset for graying hair was 30.87±11.39. Three patients (37.5%) had a history of premature hair graying. All the patients dyed their hair, and the mean age of hair dyeing was 31.5±10.50.

Conclusion: Perifollicular erythema and perifollicular scaling are important trichoscopic features of FFA. Environmental factors, autoimmune processes, and hormonal factors play a role in the development of FFA in genetically predisposed individuals. Premature hair graying and/or use of hair dyes (especially at early ages) can be a triggering or etiopathogenic factor for FFA.

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Primary Language en
Subjects General and Internal Medicine
Journal Section Research article
Authors

Orcid: 0000-0001-5069-044X
Author: Güldehan ATIŞ (Primary Author)
Institution: University of Health Sciences, Haydarpaşa Numune Training and Research Hospital
Country: Turkey


Author: Zeynep ALTAN FERHATOĞLU
Institution: University of Health Sciences, Sultan Abdülhamid Han Training and Research Hospital
Country: Turkey


Dates

Publication Date : September 1, 2018

Bibtex @research article { josam411086, journal = {Journal of Surgery and Medicine}, issn = {}, eissn = {2602-2079}, address = {jsurgmed@gmail.com}, publisher = {Fatih BAŞAK}, year = {2018}, volume = {2}, pages = {197 - 200}, doi = {10.28982/josam.411086}, title = {Review of clinical and demographic features of frontal fibrosing alopecia}, key = {cite}, author = {Atış, Güldehan and Altan Ferhatoğlu, Zeynep} }
APA Atış, G , Altan Ferhatoğlu, Z . (2018). Review of clinical and demographic features of frontal fibrosing alopecia . Journal of Surgery and Medicine , 2 (3) , 197-200 . DOI: 10.28982/josam.411086
MLA Atış, G , Altan Ferhatoğlu, Z . "Review of clinical and demographic features of frontal fibrosing alopecia" . Journal of Surgery and Medicine 2 (2018 ): 197-200 <https://jsurgmed.com/en/pub/issue/36726/411086>
Chicago Atış, G , Altan Ferhatoğlu, Z . "Review of clinical and demographic features of frontal fibrosing alopecia". Journal of Surgery and Medicine 2 (2018 ): 197-200
RIS TY - JOUR T1 - Review of clinical and demographic features of frontal fibrosing alopecia AU - Güldehan Atış , Zeynep Altan Ferhatoğlu Y1 - 2018 PY - 2018 N1 - doi: 10.28982/josam.411086 DO - 10.28982/josam.411086 T2 - Journal of Surgery and Medicine JF - Journal JO - JOR SP - 197 EP - 200 VL - 2 IS - 3 SN - -2602-2079 M3 - doi: 10.28982/josam.411086 UR - https://doi.org/10.28982/josam.411086 Y2 - 2018 ER -
EndNote %0 Journal of Surgery and Medicine Review of clinical and demographic features of frontal fibrosing alopecia %A Güldehan Atış , Zeynep Altan Ferhatoğlu %T Review of clinical and demographic features of frontal fibrosing alopecia %D 2018 %J Journal of Surgery and Medicine %P -2602-2079 %V 2 %N 3 %R doi: 10.28982/josam.411086 %U 10.28982/josam.411086
ISNAD Atış, Güldehan , Altan Ferhatoğlu, Zeynep . "Review of clinical and demographic features of frontal fibrosing alopecia". Journal of Surgery and Medicine 2 / 3 (September 2018): 197-200 . https://doi.org/10.28982/josam.411086
AMA Atış G , Altan Ferhatoğlu Z . Review of clinical and demographic features of frontal fibrosing alopecia. J Surg Med. 2018; 2(3): 197-200.
Vancouver Atış G , Altan Ferhatoğlu Z . Review of clinical and demographic features of frontal fibrosing alopecia. Journal of Surgery and Medicine. 2018; 2(3): 197-200.
IEEE G. Atış and Z. Altan Ferhatoğlu , "Review of clinical and demographic features of frontal fibrosing alopecia", Journal of Surgery and Medicine, vol. 2, no. 3, pp. 197-200, Sep. 2018, doi:10.28982/josam.411086