Sexual dysfunction and associated risk factors in multiple sclerosis

Mesrure Köseoğlu; Rabia Gökçen Gözübatık Çelik; Mesude Tutuncu; Ayhan Bingöl; Bahar Erbas; Duygu Deringöl; Dilek Ataklı

doi:10.28982/josam.800830

Authors

Mesrure Köseoğlu Sağlık Bilimleri Üniversitesi, Bakırköy Prof Dr. Mazhar Osman Ruh Sağlığı ve Sinir hastalıkları Eğitim ve Araştırma Hastanesi Nöroloji Bölümü, İstanbul,Turkiye https://orcid.org/0000-0003-0469-0064
Rabia Gökçen Gözübatık Çelik https://orcid.org/0000-0002-8186-8703
Mesude Tutuncu Sağlık Bilimleri Üniversitesi, Bakırköy Prof Dr. Mazhar Osman Ruh Sağlığı ve Sinir hastalıkları Eğitim ve Araştırma Hastanesi Nöroloji Bölümü, İstanbul,Turkiye https://orcid.org/0000-0002-1176-3156
Ayhan Bingöl Behavioral Change Academy, Istanbul, Turkey https://orcid.org/0000-0002-6024-6550
Bahar Erbas 3Deparment of Pharmacology, Demiroglu Bilim University Medical Faculty and Neurology Clinic, İstanbul Florence Nightingale Hospital https://orcid.org/0000-0002-6125-7761
Duygu Deringöl Sağlık Bilimleri Üniversitesi, Bakırköy Prof Dr Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim Ve Araştırma Hastanesi Nöroloji Bölümü, İstanbul, Turkiye https://orcid.org/0000-0002-0921-3905
Dilek Ataklı Sağlık Bilimleri Üniversitesi, Bakırköy Prof Dr. Mazhar Osman Ruh Sağlığı ve Sinir hastalıkları Eğitim ve Araştırma Hastanesi Nöroloji Bölümü, İstanbul,Turkiye https://orcid.org/0000-0001-6458-8374

DOI:

https://doi.org/10.28982/josam.800830

Keywords:

multiple sclerosis, sexual dysfunction, cognitive impairment, depression

Abstract

Aim: Sexual dysfunction (SD) is quite common in multiple sclerosis (MS), and exhibits a multifactorial pattern. This study was set out to evaluate the frequency of SD and explore the related factors to support the quality of MS patients’ lives. Methods: This cross-sectional study included 96 volunteer RRMS patients between 18 and 60 years of age who were diagnosed with MS according to the Mc Donald criteria between 2018 and 2019 in our hospital. Multiple sclerosis intimacy and sexuality questionnaire-19 (MSISQ-19), Arizona Sexual Experience Scale (ASEX), Multiple Sclerosis Inventory of Cognition (MUSIC) and Beck Depression Inventory (BDI) questionnaires were used. Results: Mean age of the patients was 38.46 (8.47) (min-max:20 – 60 years) years, and mean disease period was 77.02 (70.62) (3–324 months) months. Mean Extended Disability Status Scale (EDSS) score was 2.1 (1.33) (0-5) with a standard deviation of 80.5%. A negative correlation was observed between MUSIC cognitive and EDSS (P=0.017; r=-0.273), and BDI scores (P=0.003; r=-0.306). A significant and positive correlation was detected between MSISQ score (P<0.001; r=0.476) and BDI (P<0.001; r=0.529) in MUSIC fatigue test results. A negative and poor correlation was found between MUSIC fatigue and MUSIC cognitive score (P<0.001; r=-0.365). In patients with depression, mean MUSIC cognitive scores were lower (P=0.009), while MUSIC fatigue scores were higher (P<0.001). Age, educational status, presence of secondary SD were independent risk factors. Conclusion: SD, a quite common condition in MS, may be decreased to increase the quality of lives of patients through treatment of psychosocial factors associated with cognitive state.

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