Effects of peri-operative administration of steroids on the blood glucose levels of patients with and without diabetes undergoing laparoscopic cholecystectomy

Duygu Demiriz Gülmez; Asu Özger Özgültekin; Osman Ekinci; Mehmet Gülmez

doi:10.28982/josam.424450

Authors

Duygu Demiriz Gülmez
Asu Özger Özgültekin
Osman Ekinci
Mehmet Gülmez

DOI:

https://doi.org/10.28982/josam.424450

Keywords:

Blood Glucose, Diabetes, Steroid

Abstract

Aim: To examine blood glucose levels in patients with and without diabetes undergoing laparoscopic cholecystectomy under general anesthesia following intravenous administration of 8 mg dexamethasone to minimize postoperative complications.

Methods: Hundred patients, 50 patients with diabetes and 50 without diabetes, who underwent laparoscopic cholecystectomy and met the inclusion criteria, were divided into 2 groups. After administration of 8 mg dexamethasone, blood glucose values were observed at the 30th and 120th min and compared between the groups.

Results: Increase in blood glucose levels at the 30- and 120-min marks were statistically significant relative to the pre-induction blood glucose levels (p=0.002 and p=0.000, respectively) in the non-diabetic group. On comparing blood glucose levels at the 30- and 120-min marks, a statistically significant increase was seen to have occurred over time (p=0.000).

Conclusion: Results of the current study showed that dexamethasone caused hyperglycemia in patients with and without diabetes the 12 h after surgery. We recommend that after administration of dexamethasone, tight monitoring of blood glucose levels should be considered.

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