Yıl 2021, Cilt 5 , Sayı 2, Sayfalar 188 - 192 2021-02-01

Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report

Burak OKYAR [1] , Fatih ALBAYRAK [2] , Bekir TORUN [3] , Nurhan ATİLLA [4] , Betül KIZILDAĞ [5] , Fatih YILDIZ [6] , Gözde YILDIRIM ÇETİN [7]


Systemic Sclerosis (SSc) is a multi-systemic connective tissue disease of unknown etiology. Although many pathological processes play a role in the basis of pulmonary hypertension (PHT) that develops secondary to SSc, vasculopathy has an important place. Chronic thromboembolic hypertension (CTEPH) is in the group 4 PHT class. CTEPH distinguishes it from other causes of PHT by having both surgical and medical treatment options. CTEPH is a pathology that develops chronically and can be overlooked due to its nonspecific symptoms. Early diagnosis and treatment can reduce morbidity and mortality. The physiopathology of vasculopathy secondary to CTEPH and vasculopathy of SSc made us suspect that similar processes operate in both diseases. The processes that cause and follow endothelial damage are similar in both diseases. If this pathophysiological mechanism can be clarified, possible new treatment options can be discovered. We diagnosed CTEPH with the examinations we performed in two of our patients with SSc and interstitial lung disease, both of which developed PHT. We aimed to discuss the immunopathogenesis with two case reports.
Scleroderma, Pulmonary Hypertension, CTEPH
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Birincil Dil en
Konular Romatoloji
Bölüm Olgu sunumu
Yazarlar

Orcid: 0000-0002-9028-9930
Yazar: Burak OKYAR
Kurum: KAHRAMANMARAS SUTCU IMAM UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, RHEUMATOLOGY
Ülke: Turkey


Orcid: 0000-0002-6052-3896
Yazar: Fatih ALBAYRAK
Kurum: KAHRAMANMARAS SUTCU IMAM UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, RHEUMATOLOGY
Ülke: Turkey


Orcid: 0000-0002-9117-9514
Yazar: Bekir TORUN
Kurum: KAHRAMANMARAS SUTCU IMAM UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, RHEUMATOLOGY
Ülke: Turkey


Orcid: 0000-0003-4127-4924
Yazar: Nurhan ATİLLA
Kurum: KAHRAMANMARAS SUTCU IMAM UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF THORACIC DISEASES
Ülke: Turkey


Orcid: 0000-0002-2567-4330
Yazar: Betül KIZILDAĞ
Kurum: KAHRAMANMARAS SUTCU IMAM UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF RADIODIAGNOSTICS
Ülke: Turkey


Orcid: 0000-0003-3628-8870
Yazar: Fatih YILDIZ
Kurum: KAHRAMANMARAS SUTCU IMAM UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, RHEUMATOLOGY
Ülke: Turkey


Orcid: 0000-0001-9680-7535
Yazar: Gözde YILDIRIM ÇETİN (Sorumlu Yazar)
Kurum: KAHRAMANMARAŞ SÜTÇÜ İMAM ÜNİVERSİTESİ TIP FAKÜLTESİ
Ülke: Turkey


Tarihler

Yayımlanma Tarihi : 1 Şubat 2021

Bibtex @olgu sunumu { josam841679, journal = {Journal of Surgery and Medicine}, issn = {}, eissn = {2602-2079}, address = {jsurgmed@gmail.com}, publisher = {Fatih BAŞAK}, year = {2021}, volume = {5}, pages = {188 - 192}, doi = {10.28982/josam.841679}, title = {Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report}, key = {cite}, author = {Okyar, Burak and Albayrak, Fatih and Torun, Bekir and Atilla, Nurhan and Kızıldağ, Betül and Yıldız, Fatih and Yıldırım Çetin, Gözde} }
APA Okyar, B , Albayrak, F , Torun, B , Atilla, N , Kızıldağ, B , Yıldız, F , Yıldırım Çetin, G . (2021). Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report . Journal of Surgery and Medicine , 5 (2) , 188-192 . DOI: 10.28982/josam.841679
MLA Okyar, B , Albayrak, F , Torun, B , Atilla, N , Kızıldağ, B , Yıldız, F , Yıldırım Çetin, G . "Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report" . Journal of Surgery and Medicine 5 (2021 ): 188-192 <http://jsurgmed.com/tr/pub/issue/60239/841679>
Chicago Okyar, B , Albayrak, F , Torun, B , Atilla, N , Kızıldağ, B , Yıldız, F , Yıldırım Çetin, G . "Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report". Journal of Surgery and Medicine 5 (2021 ): 188-192
RIS TY - JOUR T1 - Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report AU - Burak Okyar , Fatih Albayrak , Bekir Torun , Nurhan Atilla , Betül Kızıldağ , Fatih Yıldız , Gözde Yıldırım Çetin Y1 - 2021 PY - 2021 N1 - doi: 10.28982/josam.841679 DO - 10.28982/josam.841679 T2 - Journal of Surgery and Medicine JF - Journal JO - JOR SP - 188 EP - 192 VL - 5 IS - 2 SN - -2602-2079 M3 - doi: 10.28982/josam.841679 UR - https://doi.org/10.28982/josam.841679 Y2 - 2021 ER -
EndNote %0 Journal of Surgery and Medicine Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report %A Burak Okyar , Fatih Albayrak , Bekir Torun , Nurhan Atilla , Betül Kızıldağ , Fatih Yıldız , Gözde Yıldırım Çetin %T Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report %D 2021 %J Journal of Surgery and Medicine %P -2602-2079 %V 5 %N 2 %R doi: 10.28982/josam.841679 %U 10.28982/josam.841679
ISNAD Okyar, Burak , Albayrak, Fatih , Torun, Bekir , Atilla, Nurhan , Kızıldağ, Betül , Yıldız, Fatih , Yıldırım Çetin, Gözde . "Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report". Journal of Surgery and Medicine 5 / 2 (Şubat 2021): 188-192 . https://doi.org/10.28982/josam.841679
AMA Okyar B , Albayrak F , Torun B , Atilla N , Kızıldağ B , Yıldız F , Yıldırım Çetin G . Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report. J Surg Med. 2021; 5(2): 188-192.
Vancouver Okyar B , Albayrak F , Torun B , Atilla N , Kızıldağ B , Yıldız F , Yıldırım Çetin G . Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report. Journal of Surgery and Medicine. 2021; 5(2): 188-192.
IEEE B. Okyar , F. Albayrak , B. Torun , N. Atilla , B. Kızıldağ , F. Yıldız ve G. Yıldırım Çetin , "Experience of chronic thromboembolic pulmonary hypertension (CTEPH) in two cases with scleroderma and immunopathogenesis overview: Case report", Journal of Surgery and Medicine, c. 5, sayı. 2, ss. 188-192, Şub. 2021, doi:10.28982/josam.841679