Yıl 2021, Cilt 5 , Sayı 1, Sayfalar 50 - 54 2021-01-01

Backgound/Aim: Myocardial infarction with non-obstructive coronary arteries (MINOCA) is an increasingly recognized entity. Recent studies have shown that MINOCA is not a benign syndrome, with younger MINOCA patients having outcomes comparable to their myocardial infarction with obstructive coronary artery disease (MI-CAD) counterparts. In this study, we will describe the demographic, clinical and angiographic characteristics of MINOCA patients in our hospital. Methods: In this retrospective cohort study, all patients who underwent coronary angiography with the diagnosis of acute coronary syndrome during September 2016-April 2019 were screened and those with MINOCA were detected. We described the demographic, clinical, and angiographic characteristics of MINOCA patients and compared the etiologic and pathophysiological mechanisms. Results: A total of 3855 patients with acute coronary syndrome were screened and 155 were diagnosed with MINOCA, with a total prevalence of 4.02%. Among them, 48.4% were female and the overall mean age was 55.04 (13.57) years. Plaque disruption was the most common cause of MINOCA (48.4%), which was followed by microvascular dysfunction and slow flow (9.7%). We compared plaque disruption and other causes to find that age (58.31 (13.76) vs 51.89 (12.68) P=0.003), hypertension (37 (48.7%) vs 25 (31.6%) P=0.034), prior coronary artery disease history (16 (21.1%) vs 2 (2.5%) P=0.001) and creatinine clearance (67.35 (IQR: 25.8) vs 74.0 (IQR: 28.58) P=0.009) were higher in patients with plaque disruption than those without. Conclusion: MINOCA is a diagnosis of exclusion with numerous potential causes. The etiological and pathophysiological mechanisms of plaque disruption are different from other causes of MINOCA and the correct treatment approach determines the prognosis.
microvascular dysfunction, MINOCA, plaque disruption, SCAD, vasospasm
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Birincil Dil en
Konular Kalp ve Kalp Damar Sistemi
Bölüm Araştırma makalesi
Yazarlar

Orcid: 0000-0002-6782-4237
Yazar: Serkan ASIL (Sorumlu Yazar)
Kurum: ANKARA T.C. SB. SBÜ. GÜLHANE EĞİTİM VE ARAŞTIRMA HASTANESİ
Ülke: Turkey


Orcid: 0000-0002-3021-8612
Yazar: Veysel Özgür BARIŞ
Kurum: GAZİANTEP DR. ERSİN ARSLAN EĞİTİM VE ARAŞTIRMA HASTANESİ
Ülke: Turkey


Orcid: 0000-0001-8702-0909
Yazar: Muhammet GENEŞ
Kurum: Gülhane Eğitim Araştırma Hastanesi Kardiyoloji Kliniği
Ülke: Turkey


Orcid: 0000-0001-8309-6076
Yazar: Hatice TAŞKAN
Kurum: 0000-0003-4092-8463
Ülke: Turkey


Orcid: 0000-0003-3659-5360
Yazar: Suat GÖRMEL
Kurum: Gülhane Eğitim Araştırma Hastanesi Kardiyoloji Kliniği
Ülke: Turkey


Orcid: 0000-0003-0949-9242
Yazar: Erkan YILDIRIM
Kurum: Gülhane Eğitim Araştırma Hastanesi Kardiyoloji Kliniği
Ülke: Turkey


Orcid: 0000-0002-8929-6850
Yazar: Yalçın GÖKOĞLAN
Kurum: GülHane Eğitim Araştırma Hastanesi Kardiyoloji Kliniği
Ülke: Turkey


Orcid: 0000-0002-7864-4952
Yazar: Murat ÇELIK
Kurum: GülHane Eğitim Araştırma Hastanesi Kardiyoloji Kliniği
Ülke: Turkey


Orcid: 0000-0003-1531-6967
Yazar: Uygar Çağdaş YÜKSEL
Kurum: GülHane Eğitim Araştırma Hastanesi Kardiyoloji Kliniği
Ülke: Turkey


Orcid: 0000-0002-5258-4269
Yazar: Hasan Kutsi KABUL
Kurum: GülHane Eğitim Araştırma Hastanesi Kardiyoloji Kliniği
Ülke: Turkey


Orcid: 0000-0003-4092-8463
Yazar: Cem BARÇIN
Kurum: GülHane Eğitim Araştırma Hastanesi Kardiyoloji Kliniği
Ülke: Turkey


Destekleyen Kurum Yok
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Tarihler

Yayımlanma Tarihi : 1 Ocak 2021

Bibtex @araştırma makalesi { josam839523, journal = {Journal of Surgery and Medicine}, issn = {}, eissn = {2602-2079}, address = {jsurgmed@gmail.com}, publisher = {Fatih BAŞAK}, year = {2021}, volume = {5}, pages = {50 - 54}, doi = {10.28982/josam.839523}, title = {Myocardial infarction with non-obstructive coronary artery disease, a retrospective cohort study: Are plaque disruption and other pathophysiological mechanisms the same disease?}, key = {cite}, author = {Asıl, Serkan and Barış, Veysel Özgür and Geneş, Muhammet and Taşkan, Hatice and Görmel, Suat and Yıldırım, Erkan and Gökoğlan, Yalçın and Çelık, Murat and Yüksel, Uygar Çağdaş and Kabul, Hasan Kutsi and Barçın, Cem} }
APA Asıl, S , Barış, V , Geneş, M , Taşkan, H , Görmel, S , Yıldırım, E , Gökoğlan, Y , Çelık, M , Yüksel, U , Kabul, H , Barçın, C . (2021). Myocardial infarction with non-obstructive coronary artery disease, a retrospective cohort study: Are plaque disruption and other pathophysiological mechanisms the same disease? . Journal of Surgery and Medicine , 5 (1) , 50-54 . DOI: 10.28982/josam.839523
MLA Asıl, S , Barış, V , Geneş, M , Taşkan, H , Görmel, S , Yıldırım, E , Gökoğlan, Y , Çelık, M , Yüksel, U , Kabul, H , Barçın, C . "Myocardial infarction with non-obstructive coronary artery disease, a retrospective cohort study: Are plaque disruption and other pathophysiological mechanisms the same disease?" . Journal of Surgery and Medicine 5 (2021 ): 50-54 <http://jsurgmed.com/tr/pub/issue/59430/839523>
Chicago Asıl, S , Barış, V , Geneş, M , Taşkan, H , Görmel, S , Yıldırım, E , Gökoğlan, Y , Çelık, M , Yüksel, U , Kabul, H , Barçın, C . "Myocardial infarction with non-obstructive coronary artery disease, a retrospective cohort study: Are plaque disruption and other pathophysiological mechanisms the same disease?". Journal of Surgery and Medicine 5 (2021 ): 50-54
RIS TY - JOUR T1 - Myocardial infarction with non-obstructive coronary artery disease, a retrospective cohort study: Are plaque disruption and other pathophysiological mechanisms the same disease? AU - Serkan Asıl , Veysel Özgür Barış , Muhammet Geneş , Hatice Taşkan , Suat Görmel , Erkan Yıldırım , Yalçın Gökoğlan , Murat Çelık , Uygar Çağdaş Yüksel , Hasan Kutsi Kabul , Cem Barçın Y1 - 2021 PY - 2021 N1 - doi: 10.28982/josam.839523 DO - 10.28982/josam.839523 T2 - Journal of Surgery and Medicine JF - Journal JO - JOR SP - 50 EP - 54 VL - 5 IS - 1 SN - -2602-2079 M3 - doi: 10.28982/josam.839523 UR - https://doi.org/10.28982/josam.839523 Y2 - 2021 ER -
EndNote %0 Journal of Surgery and Medicine Myocardial infarction with non-obstructive coronary artery disease, a retrospective cohort study: Are plaque disruption and other pathophysiological mechanisms the same disease? %A Serkan Asıl , Veysel Özgür Barış , Muhammet Geneş , Hatice Taşkan , Suat Görmel , Erkan Yıldırım , Yalçın Gökoğlan , Murat Çelık , Uygar Çağdaş Yüksel , Hasan Kutsi Kabul , Cem Barçın %T Myocardial infarction with non-obstructive coronary artery disease, a retrospective cohort study: Are plaque disruption and other pathophysiological mechanisms the same disease? %D 2021 %J Journal of Surgery and Medicine %P -2602-2079 %V 5 %N 1 %R doi: 10.28982/josam.839523 %U 10.28982/josam.839523
ISNAD Asıl, Serkan , Barış, Veysel Özgür , Geneş, Muhammet , Taşkan, Hatice , Görmel, Suat , Yıldırım, Erkan , Gökoğlan, Yalçın , Çelık, Murat , Yüksel, Uygar Çağdaş , Kabul, Hasan Kutsi , Barçın, Cem . "Myocardial infarction with non-obstructive coronary artery disease, a retrospective cohort study: Are plaque disruption and other pathophysiological mechanisms the same disease?". Journal of Surgery and Medicine 5 / 1 (Ocak 2021): 50-54 . https://doi.org/10.28982/josam.839523
AMA Asıl S , Barış V , Geneş M , Taşkan H , Görmel S , Yıldırım E , Gökoğlan Y , Çelık M , Yüksel U , Kabul H , Barçın C . Myocardial infarction with non-obstructive coronary artery disease, a retrospective cohort study: Are plaque disruption and other pathophysiological mechanisms the same disease?. J Surg Med. 2021; 5(1): 50-54.
Vancouver Asıl S , Barış V , Geneş M , Taşkan H , Görmel S , Yıldırım E , Gökoğlan Y , Çelık M , Yüksel U , Kabul H , Barçın C . Myocardial infarction with non-obstructive coronary artery disease, a retrospective cohort study: Are plaque disruption and other pathophysiological mechanisms the same disease?. Journal of Surgery and Medicine. 2021; 5(1): 50-54.
IEEE S. Asıl , V. Barış , M. Geneş , H. Taşkan , S. Görmel , E. Yıldırım , Y. Gökoğlan , M. Çelık , U. Yüksel , H. Kabul ve C. Barçın , "Myocardial infarction with non-obstructive coronary artery disease, a retrospective cohort study: Are plaque disruption and other pathophysiological mechanisms the same disease?", Journal of Surgery and Medicine, c. 5, sayı. 1, ss. 50-54, Oca. 2021, doi:10.28982/josam.839523