Year 2020, Volume 4 , Issue 11, Pages 952 - 955 2020-11-01

Hematolojik enflamasyon belirteçleri erken gebelik kaybının göstergesi olabilir mi?
Can hematologic inflammation markers be the indicator of early pregnancy loss?

Taylan ONAT [1] , Demet AYDOĞAN KIRMIZI [2] , Melike DEMİR ÇALTEKİN [3] , Emre BAŞER [4] , Ethem Serdar YALVAÇ [5]


Amaç: İnsan gebeliklerinin yaklaşık % 50'sinde gebelik kaybı meydana gelmektedir ve erken gebeliğin en sık görülen komplikasyonudur. Bu çalışmanın amacı, erken gebelik kaybı ile inflamasyon arasındaki ilişkiyi hematolojik belirteçler ile değerlendirmektir. Yöntemler: Çalışma Ocak 2016 / Mart 2019 tarihleri arasında kliniğimizde gerçekleşmiş olan erken gebelik kaybı olgularını değerlendiren, olgu-kontrol çalışmasıdır. Erken gebelik kaybı grubu 94 hasta, kontrol grubu ise 104 miadında doğum yapmış kadından oluşturuldu. Grupların demografik verilerine ve tam kan sayımı sonuçlarına hasta dosyaları ve hastane bilgi yönetim sistemi taranarak ulaşıldı. Bulgular: İki grup arasında yaş ve vücut kitle indeksi açısından istatistiksel olarak anlamlı bir fark yoktu. Abortus grubunda gebelik kayıpları ortalama 9,03 (3,62) haftada gerçekleşmiştir. Abortus grubunda kontrol grubuna kıyasla platelet sayısı (P=0,003), NLR (P=0,036), PLR (P=0,032) ve plateletkrit (P=0,007) yüksek olarak saptanmıştır. Diğer taraftan, LMR (P=0,034) abortus grubunda düşük olarak saptanmıştır. Sonuçlar: Hematolojik enflamasyon parametreleri kolay ulaşılabilen ve maliyet olarak ucuz tetkiklerdir. Çalışmamızda bu parametrelerin erken gebelik kaybını öngörme başarısı değerlendirilmiş ve sonuç olarak, gruplar arasında hematolojik inflamasyon belirteçlerinde anlamlı farklılıklar olmasına rağmen, bu belirteçlerin duyarlılık ve özgüllüğünün düşük olduğu bulunmuştur.
Aim: Pregnancy loss occurs in 50% of human pregnancies and is the most common complication of early pregnancy. The aim of this study is to evaluate the relationship between early pregnancy loss and inflammation with hematological markers. Methods: This case-control study was carried out between January 2016-March 2019 in our clinic to evaluate the cases of early pregnancy loss. The early pregnancy loss group consisted of 94 patients, while the control group consisted of 104 women giving normal birth. Demographic data and complete blood count results of the groups were obtained from the patient files and hospital information management systems. Results: There were no statistically significant differences in terms of age and body mass index between the two groups. Pregnancy losses in the abortion group occurred at an average of 9.03 (3.62) weeks. In the abortus group, platelet count (P=0.003), NLR (P=0.036), PLR (P=0.032) and plateletcrit (P=0.007) were higher, while LMR (P=0.034) was lower, compared to the control group. Conclusions: Hematological inflammation parameters are easy to perform and cost-effective examinations. In our study, the success of these parameters to predict early pregnancy loss was evaluated, and it was found that although there are significant differences in hematological inflammation markers between the groups, the sensitivity and specificity of these markers are low.
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Primary Language en
Subjects Obstetrics and Gynecology
Journal Section Research article
Authors

Orcid: 0000-0002-8920-1444
Author: Taylan ONAT (Primary Author)
Institution: BOZOK UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES
Country: Turkey


Orcid: 0000-0001-7849-8214
Author: Demet AYDOĞAN KIRMIZI
Institution: BOZOK UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES
Country: Turkey


Orcid: 0000-0001-8797-7794
Author: Melike DEMİR ÇALTEKİN
Institution: BOZOK UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES
Country: Turkey


Orcid: 0000-0003-3828-9631
Author: Emre BAŞER
Institution: BOZOK UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES
Country: Turkey


Orcid: 0000-0001-9941-4999
Author: Ethem Serdar YALVAÇ
Institution: BOZOK UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES
Country: Turkey


Dates

Publication Date : November 1, 2020

Bibtex @research article { josam736881, journal = {Journal of Surgery and Medicine}, issn = {}, eissn = {2602-2079}, address = {jsurgmed@gmail.com}, publisher = {Fatih BAŞAK}, year = {2020}, volume = {4}, pages = {952 - 955}, doi = {10.28982/josam.736881}, title = {Can hematologic inflammation markers be the indicator of early pregnancy loss?}, key = {cite}, author = {Onat, Taylan and Aydoğan Kırmızı, Demet and Demir Çaltekin, Melike and Başer, Emre and Yalvaç, Ethem Serdar} }
APA Onat, T , Aydoğan Kırmızı, D , Demir Çaltekin, M , Başer, E , Yalvaç, E . (2020). Can hematologic inflammation markers be the indicator of early pregnancy loss? . Journal of Surgery and Medicine , 4 (11) , 952-955 . DOI: 10.28982/josam.736881
MLA Onat, T , Aydoğan Kırmızı, D , Demir Çaltekin, M , Başer, E , Yalvaç, E . "Can hematologic inflammation markers be the indicator of early pregnancy loss?" . Journal of Surgery and Medicine 4 (2020 ): 952-955 <http://jsurgmed.com/en/pub/issue/57748/736881>
Chicago Onat, T , Aydoğan Kırmızı, D , Demir Çaltekin, M , Başer, E , Yalvaç, E . "Can hematologic inflammation markers be the indicator of early pregnancy loss?". Journal of Surgery and Medicine 4 (2020 ): 952-955
RIS TY - JOUR T1 - Can hematologic inflammation markers be the indicator of early pregnancy loss? AU - Taylan Onat , Demet Aydoğan Kırmızı , Melike Demir Çaltekin , Emre Başer , Ethem Serdar Yalvaç Y1 - 2020 PY - 2020 N1 - doi: 10.28982/josam.736881 DO - 10.28982/josam.736881 T2 - Journal of Surgery and Medicine JF - Journal JO - JOR SP - 952 EP - 955 VL - 4 IS - 11 SN - -2602-2079 M3 - doi: 10.28982/josam.736881 UR - https://doi.org/10.28982/josam.736881 Y2 - 2020 ER -
EndNote %0 Journal of Surgery and Medicine Can hematologic inflammation markers be the indicator of early pregnancy loss? %A Taylan Onat , Demet Aydoğan Kırmızı , Melike Demir Çaltekin , Emre Başer , Ethem Serdar Yalvaç %T Can hematologic inflammation markers be the indicator of early pregnancy loss? %D 2020 %J Journal of Surgery and Medicine %P -2602-2079 %V 4 %N 11 %R doi: 10.28982/josam.736881 %U 10.28982/josam.736881
ISNAD Onat, Taylan , Aydoğan Kırmızı, Demet , Demir Çaltekin, Melike , Başer, Emre , Yalvaç, Ethem Serdar . "Can hematologic inflammation markers be the indicator of early pregnancy loss?". Journal of Surgery and Medicine 4 / 11 (November 2020): 952-955 . https://doi.org/10.28982/josam.736881
AMA Onat T , Aydoğan Kırmızı D , Demir Çaltekin M , Başer E , Yalvaç E . Can hematologic inflammation markers be the indicator of early pregnancy loss?. J Surg Med. 2020; 4(11): 952-955.
Vancouver Onat T , Aydoğan Kırmızı D , Demir Çaltekin M , Başer E , Yalvaç E . Can hematologic inflammation markers be the indicator of early pregnancy loss?. Journal of Surgery and Medicine. 2020; 4(11): 952-955.
IEEE T. Onat , D. Aydoğan Kırmızı , M. Demir Çaltekin , E. Başer and E. Yalvaç , "Can hematologic inflammation markers be the indicator of early pregnancy loss?", Journal of Surgery and Medicine, vol. 4, no. 11, pp. 952-955, Nov. 2020, doi:10.28982/josam.736881