Year 2020, Volume 4 , Issue 5, Pages 367 - 370 2020-05-01

Clinical and basic cardiovascular features of patients with COVID-19 admitted to a tertiary care center in Turkey
Türkiye’de bir üçüncü basamak sağlık merkezine başvuran COVID-19’lu hastaların klinik ve temel kardiyovasküler özellikleri

Sabür ZENGİN [1] , Sema AVCI [2] , Seyhan YILMAZ [3]


Aim: COVID-19 is a new zoonotic infectious disease that can cause acute respiratory failure, which first occurred in Wuhan, China in December 2019. The aim of study was to analyze cases with COVID-19 admitted to a tertiary care center in Turkey.
Methods: We evaluated demographic characteristics, clinical symptoms or signs, comorbidities, laboratory results, chest computed tomography (CT) findings and outcomes including hospitalization, intensive care unit (ICU) admission and survival of 49 patients (20 females, 29 males) diagnosed with COVID-19 disease.
Results: Twenty (40.9%) of the cases were female and 29 (59.1%) were male. The mean age of the patients was 56.20 (17.65) years. The most common symptom was cough (75.5%). Hypertension (26.5%) was the most prevalent comorbid disease. Troponin I result of 42 (85.7%) patients were negative (reference value <0.1 ng/mL). Ten patients (18.4%) were admitted to the ICU and overall mortality rate was 4.1% (n=2). The important characteristics of two non-survivors were as follows: 1) A 67-year-old-man, high fever (38.50C), current smoker, diabetes mellitus (+), chronic obstructive pulmonary disease (COPD) (+), congestive heart failure (+), first admission to ICU, bilateral infiltration on chest CT, troponin I: 4.01 ng/L. 2) A 38-year-old-man, current smoker, COPD (+), first admission to ICU and high CRP (120.86 m/L).
Conclusion: The clinical parameters that determine the prognosis of COVID-19 are currently acute respiratory tract exacerbation and accompanying cardiovascular diseases such as hypertension and coronary artery disease. Cardiac enzyme monitoring is important in patients with cardiovascular risk factors.

Amaç: COVID-19 akut solunum yetmezliğine neden olabilen, ilk kez Aralık 2019’da Çin’in Wuhan şehrinde ortaya çıkan yeni zoonotik bir enfeksiyöz hastalıktır. Bu çalışmanın amacı Türkiye’de bir üçüncü basamak hastaneye başvuran COVID-19’lu hastaları analiz etmektir.
Yöntemler: Çalışmada, COVID-19 hastalık tanısı almış 49 hastanın (20 kadın, 29 erkek) demografik özellikleri, klinik semptom ve bulguları, komorbiditeleri, laboratuar sonuçları, toraks bilgisayarlı tomografi (BT) bulguları ve sağkalım, yoğun bakım ünitesine (YBÜ) ve servis yatışlarını değerlendirdik.
Bulgular: Vakaların 20’si (%40,9) kadın ve 29’u (%59,1) erkekti. Hastaların ortalama yaşı 56,20 (17,65) idi. En sık görülen semptom öksürüktü (%75,5). Hipertansiyon en sık eşlik eden hastalıktı (%26,5). 42 hastanın (%85,7) troponin I değeri negatifti (referans değer <0,1 ng/mL). 10 hasta YBÜ’ye başvurmuştu ve genel mortalite oranı %4,1 idi (n=2). Ölen iki hastanın önemli karakteristik özellikleri şöyleydi: i) 67 yaş erkek hasta, yüksek ateş (38,50C), sigara içici, diabetes mellitus (+), kronik obstrüktif akciğer hastalığı (KOAH) (+), konjestif kalp yetmezliği (+), ilk başvuru YBÜ’ye, toraks BT’de bilateral infiltrasyon ve troponin I (4,01 ng/L). ii) 38 yaş erkek hasta, sigara içici, KOAH (+), ilk başvuru YBÜ’ye ve yüksek c-reaktif protein (120,86 m/L).
Sonuç: Mevcut bilgilerimize göre COVID-19’da prognozu belirleyen klinik parametreler akut solunum yolu alevlenmesi ve hipertansiyon veya koroner arter hastalığı gibi kardiyovasküler hastalıkların eşlik etmesidir. Kardiyovasküler risk faktörleri olan hastalarda kardiyak enzim takibi önemlidir.

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Primary Language en
Subjects Respiratory System
Journal Section Research article
Authors

Orcid: 0000-0003-4966-2681
Author: Sabür ZENGİN
Institution: Sabuncuoğlu Şerefeddin Eğitim ve Araştırma Hastanesi
Country: Turkey


Orcid: 0000-0002-0992-4192
Author: Sema AVCI (Primary Author)
Institution: Amasya Üniversitesi
Country: Turkey


Orcid: 0000-0003-0865-0721
Author: Seyhan YILMAZ
Institution: Amasya Üniversitesi
Country: Turkey


Dates

Publication Date : May 1, 2020

Bibtex @research article { josam727935, journal = {Journal of Surgery and Medicine}, issn = {}, eissn = {2602-2079}, address = {jsurgmed@gmail.com}, publisher = {Fatih BAŞAK}, year = {2020}, volume = {4}, pages = {367 - 370}, doi = {10.28982/josam.727935}, title = {Clinical and basic cardiovascular features of patients with COVID-19 admitted to a tertiary care center in Turkey}, key = {cite}, author = {Zengi̇n, Sabür and Avcı, Sema and Yılmaz, Seyhan} }
APA Zengi̇n, S , Avcı, S , Yılmaz, S . (2020). Clinical and basic cardiovascular features of patients with COVID-19 admitted to a tertiary care center in Turkey . Journal of Surgery and Medicine , 4 (5) , 367-370 . DOI: 10.28982/josam.727935
MLA Zengi̇n, S , Avcı, S , Yılmaz, S . "Clinical and basic cardiovascular features of patients with COVID-19 admitted to a tertiary care center in Turkey" . Journal of Surgery and Medicine 4 (2020 ): 367-370 <http://jsurgmed.com/en/pub/issue/54145/727935>
Chicago Zengi̇n, S , Avcı, S , Yılmaz, S . "Clinical and basic cardiovascular features of patients with COVID-19 admitted to a tertiary care center in Turkey". Journal of Surgery and Medicine 4 (2020 ): 367-370
RIS TY - JOUR T1 - Clinical and basic cardiovascular features of patients with COVID-19 admitted to a tertiary care center in Turkey AU - Sabür Zengi̇n , Sema Avcı , Seyhan Yılmaz Y1 - 2020 PY - 2020 N1 - doi: 10.28982/josam.727935 DO - 10.28982/josam.727935 T2 - Journal of Surgery and Medicine JF - Journal JO - JOR SP - 367 EP - 370 VL - 4 IS - 5 SN - -2602-2079 M3 - doi: 10.28982/josam.727935 UR - https://doi.org/10.28982/josam.727935 Y2 - 2020 ER -
EndNote %0 Journal of Surgery and Medicine Clinical and basic cardiovascular features of patients with COVID-19 admitted to a tertiary care center in Turkey %A Sabür Zengi̇n , Sema Avcı , Seyhan Yılmaz %T Clinical and basic cardiovascular features of patients with COVID-19 admitted to a tertiary care center in Turkey %D 2020 %J Journal of Surgery and Medicine %P -2602-2079 %V 4 %N 5 %R doi: 10.28982/josam.727935 %U 10.28982/josam.727935
ISNAD Zengi̇n, Sabür , Avcı, Sema , Yılmaz, Seyhan . "Clinical and basic cardiovascular features of patients with COVID-19 admitted to a tertiary care center in Turkey". Journal of Surgery and Medicine 4 / 5 (May 2020): 367-370 . https://doi.org/10.28982/josam.727935
AMA Zengi̇n S , Avcı S , Yılmaz S . Clinical and basic cardiovascular features of patients with COVID-19 admitted to a tertiary care center in Turkey. J Surg Med. 2020; 4(5): 367-370.
Vancouver Zengi̇n S , Avcı S , Yılmaz S . Clinical and basic cardiovascular features of patients with COVID-19 admitted to a tertiary care center in Turkey. Journal of Surgery and Medicine. 2020; 4(5): 367-370.