Year 2020, Volume 4 , Issue 1, Pages 99 - 101 2020-01-02

16 yaşındaki ergende tek seferde yüksek doz duloksetin kullanımı ortaya çıkan işitsel, görsel ve dokunsal halüsinasyonlar
Auditory, visual and tactile hallucinations in a 16-year-old adolescent with high-dose duloxetine at one time

Sefa COSGUN [1]


Duloksetin dual etkili serotonin-noradrenalin geri alım inhibitörüdür. Erişkinlerde Major Depresif Bozukluk (MDD), Yaygın Anksiyete Bozukluğu (GAD), Diyabetik Nöropatik Ağrı, Fibromiyalji, Kronik İskelet Kas Ağrısı tanılarında, çocuk ve ergenlerde GAD için FDA onayı vardır. Bu yazıda, baş ağrıları olduğu için toplam 330 mg/gün duloksetin içen sonrasında halüsinasyonları başladığı için acil servise başvuran 16 yaşındaki kadın hasta sunulacaktır. Halüsinasyonların serotonerjik sistem ve noradrenalin transport sisteminin inhibisyonu sonucunda dopamin artışına bağlı olabileceği düşünülmektedir. Bu yazı, duloksetinin, çocuk ve ergenlerdeki farmakokinetik ve farmakodinamik etkileri açısından literatüre katkı sağlayacağı düşünülmüştür.

Duloxetine is a dual-acting serotonin-noradrenaline reuptake inhibitor. It has FDA approval for the diagnosis of Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Diabetic Neuropathic Pain, Fibromyalgia, Chronic Skeletal Muscle Pain in adults, and GAD in children and adolescents. This article presents a 16-year-old female patient referred to the emergency department with hallucinations starting after she took a total of 330 mg/day duloxetine for headaches. It is thought that her experienced hallucinations may be due to increased dopamine, as a result of inhibition of serotonergic system and noradrenaline transport system. It is thought that this article will contribute to the literature in terms of pharmacokinetic and pharmacodynamic effects of duloxetine in children and adolescents.

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Primary Language en
Subjects Psychiatry
Journal Section Case report
Authors

Orcid: 0000-0003-2843-6554
Author: Sefa COSGUN (Primary Author)
Institution: SBÜ. VAN EĞİTİM VE ARAŞTIRMA HASTANESİ
Country: Turkey


Dates

Publication Date : January 2, 2020

Bibtex @case report { josam627206, journal = {Journal of Surgery and Medicine}, issn = {}, eissn = {2602-2079}, address = {jsurgmed@gmail.com}, publisher = {Fatih BAŞAK}, year = {2020}, volume = {4}, pages = {99 - 101}, doi = {10.28982/josam.627206}, title = {Auditory, visual and tactile hallucinations in a 16-year-old adolescent with high-dose duloxetine at one time}, key = {cite}, author = {Cosgun, Sefa} }
APA Cosgun, S . (2020). Auditory, visual and tactile hallucinations in a 16-year-old adolescent with high-dose duloxetine at one time . Journal of Surgery and Medicine , 4 (1) , 99-101 . DOI: 10.28982/josam.627206
MLA Cosgun, S . "Auditory, visual and tactile hallucinations in a 16-year-old adolescent with high-dose duloxetine at one time" . Journal of Surgery and Medicine 4 (2020 ): 99-101 <http://jsurgmed.com/en/pub/issue/51597/627206>
Chicago Cosgun, S . "Auditory, visual and tactile hallucinations in a 16-year-old adolescent with high-dose duloxetine at one time". Journal of Surgery and Medicine 4 (2020 ): 99-101
RIS TY - JOUR T1 - Auditory, visual and tactile hallucinations in a 16-year-old adolescent with high-dose duloxetine at one time AU - Sefa Cosgun Y1 - 2020 PY - 2020 N1 - doi: 10.28982/josam.627206 DO - 10.28982/josam.627206 T2 - Journal of Surgery and Medicine JF - Journal JO - JOR SP - 99 EP - 101 VL - 4 IS - 1 SN - -2602-2079 M3 - doi: 10.28982/josam.627206 UR - https://doi.org/10.28982/josam.627206 Y2 - 2020 ER -
EndNote %0 Journal of Surgery and Medicine Auditory, visual and tactile hallucinations in a 16-year-old adolescent with high-dose duloxetine at one time %A Sefa Cosgun %T Auditory, visual and tactile hallucinations in a 16-year-old adolescent with high-dose duloxetine at one time %D 2020 %J Journal of Surgery and Medicine %P -2602-2079 %V 4 %N 1 %R doi: 10.28982/josam.627206 %U 10.28982/josam.627206
ISNAD Cosgun, Sefa . "Auditory, visual and tactile hallucinations in a 16-year-old adolescent with high-dose duloxetine at one time". Journal of Surgery and Medicine 4 / 1 (January 2020): 99-101 . https://doi.org/10.28982/josam.627206
AMA Cosgun S . Auditory, visual and tactile hallucinations in a 16-year-old adolescent with high-dose duloxetine at one time. J Surg Med. 2020; 4(1): 99-101.
Vancouver Cosgun S . Auditory, visual and tactile hallucinations in a 16-year-old adolescent with high-dose duloxetine at one time. Journal of Surgery and Medicine. 2020; 4(1): 99-101.