The postoperative follow-up of varicose vein treatment with N-2-butyl cyanoacrylate application: A case series



N-2-butyl cyanoacrylate, Varicose vein, Treatment, Non-degradable


N-2-butyl cyanoacrylate application to varicose veins is a novel minimally invasive method for varicose veins. The non-requirement for tumescent anesthesia is the most advantageous feature of this method. However, the intravascular persistence of the administered substance after the procedure has not been evaluated. In this study, the intravascular persistence of N-2-butyl cyanoacrylate was evaluated in the 6th month of administration. Three cases who underwent great saphenous vein ablation treatment with N-2-butyl cyanoacrylate were included in the study. The early postoperative and midterm (6th month) Doppler ultrasonography results were compared. The venous reflux in the sapheno-femoral junction (SFJ) level was totally treated after N-2-butyl cyanoacrylate administration in all patients. Ultrasonography revealed fully filled N-2-butyl cyanoacrylate at the treated levels of the saphenous veins. Similarly, 6th month’s ultrasonography examinations revealed that N-2-butyl cyanoacrylate filled the great saphenous vein at the same level. It was observed that the rate of the vessel closed with N-2-butyl cyanoacrylate remained unchanged during six months. According to our results, intravenous N-2-butyl cyanoacrylate remains the same as at the time of administration without any degradation.


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Case Report

How to Cite

Hafız E. The postoperative follow-up of varicose vein treatment with N-2-butyl cyanoacrylate application: A case series. J Surg Med [Internet]. 2021 Oct. 1 [cited 2022 Nov. 28];5(10):1076-8. Available from: