Effect of air pollution, air pressure and air temperature on new onset pulmonary thromboembolism: A case-control study

Engin Akgül; Gündüz Yümün

doi:10.28982/josam.822731

Authors

Engin Akgül https://orcid.org/0000-0001-7361-0430
Gündüz Yümün Corlu State Hospital, Department of Cardiovascular Surgery https://orcid.org/0000-0002-1503-329X

DOI:

https://doi.org/10.28982/josam.822731

Keywords:

Particulate matter, PM10, SO2, air pressure, pulmonary thromboembolism, air pollution

Abstract

Aim: Air pollution affects many people globally and there are allegations and studies that it leads to serious health problems, such as pulmonary thromboembolism. In this study, we investigated the possible relationship between air conditions and pulmonary thromboembolism. Methods: This study was carried out by archive scanning. Patients with acute dyspnea who were shown to have PE by contrast-enhanced CT were included in the analysis. Patients with a history of trauma, malignancy, recent surgical intervention, or immobility were excluded from the study. On the day of complaints, Particulate matter 10 (PM10), sulfur dioxide (SO2), air temperature and air pressure values were obtained online from the relevant institution of Environment and Urban Ministry. These 215 patients’ data were then evaluated statistically. Results: Results suggest that the incidence of pulmonary embolism was higher on days when PM10 (P<0.001) and air pressure levels were high (P<0.001). However, SO2 and temperature were not directly associated with the frequency of pulmonary embolism (P=0.422, P=0.778). Conclusion: In light of this study, it can be said that air quality may have different consequences on human health. Elevated PM10 and air pressure levels can affect the circulatory system negatively and aggravate thromboembolism.

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References

Schinder A, Panagiotakos D, Picciotto S, Katsouyannı K, Lövel H. Air temperature and inflammatory responses in myocardial infarction survivors Epidemiology. 2008 May;19(3):391-400.

Franchini M, Mannucci PM. Particulate air pollution and cardiovascular risk: short-term and long-term effects Semin Thromb Hemost. 2009 Oct;35(7):665-70.

Stein PD, Kayalı F, Olson RE. Analysis of occurrence of venous thromboembolic disease in the four seasons Am J Cardiol. 2004 Feb 15;93(4):511-3.

Clauss R, Mayes J, Hilton P, Lawrenson R. The influence of weather and environment on pulmonary embolism: pollutants and fossil fuels Med Hypotheses. 2005;64(6):1198-201.

Anar C, Inal T, Erol S, Polat G, Unsal I, Ediboglu Ö, et al. Are Meteorological Parameters a Risk Factor for Pulmonary Embolism? A Retrospective Analysis of 530 Patients Balkan Med J. 2015 Jul;32(3):279-84.

Dominici F, McDermott A, Daniels M, Zeger SL, Samet JM. Revised analyses of the National Morbidity, Mortality, and Air Pollution Study: mortality among residents of 90 cities J Toxicol Environ Health A. 2005 Jul 9-23;68(13-14):1071-92.

Peters A, Von Klot S, Heier M, Trentinaglia I, Hormann A. Exposure to traffic and the onset of myocardial infarction N Engl J Med. 2004 Oct 21;351(17):1721-30.

Chuang GC, Yang Z, Westbrook DG, Pompilius M, Ballinger CA. Pulmonary ozone exposure induces vascular dysfunction, mitochondrial damage, and atherogenesis Am J Physiol Lung Cell Mol Physiol. 2009 Aug;297(2):L209-16.

Wang XB, Jin HF, Tang CS, Du JB. The biological effect of endogenous sulfur dioxide in the cardiovascular system Eur J Pharmacol. 2011 Nov 16;670(1):1-6.

Oztuna F, Ozsu S, Topbas M, Bulbul Y, Kosucu P, Ozlu T. Meteorological parameters and seasonal variations in pulmonary thromboembolism Am J Emerg Med. 2008 Nov;26(9):1035-41.

Törö K, Pongracz R, Bartholy J, Varadi TA, Marcsa B, Szilagyi B, et al. Evaluation of meteorological and epidemiological characteristics of fatal pulmonary embolism.Int J Biometeorol. 2016 Mar;60(3):351-9.

DE Miguel-diez J, Jimenza R, Lopez de Andreas A. Analysis of environmental risk factors for pulmonary embolism: A case-crossover study (2001-2013). Eur J Intern Med. 2016 Jun;31:55-61.

Bhaskaran K, Hajat S, Haines A, Herrett E, Wilkinson P, Smeeth L. Effects of ambient temperature on the incidence of myocardial infarction Heart. 2009 Nov;95(21):1760-9.

Lelieved J, Evans JS, Fnais M, Giannadaki D, Pozzer A. The contribution of outdoor air pollution sources to premature mortality on a global scale Nature. 2015 Sep 17;525(7569):367-71.

Pope CA, Dockery DW. Health effects of fine particulate air pollution: lines that connectJ Air Waste Manag Assoc. 2006 Jun;56(6):709-42.

Atkinson RW, Carey IM, Kent AJ, van Staa TP, Anderson HR, Cook DG. Long-term exposure to outdoor air pollution and incidence of cardiovascular diseases. Epidemiology 2013;24:44-53.

Miller KA, Siscovick DS, Sheppard L, Shepherd K, Sullivan JH, Anderson GL, et al. Longterm exposure to air pollution and incidence of cardiovascular events in women. N Engl J Med 2007;356:447-58.

Rosenlund M, Berglind N, Pershagen G, Hallqvist J, Jonson T, Bellander T. Long-term exposure to urban air pollution and myocardial infarction. Epidemiology 2006;17:383-90.

Meng X, Ma Y, Chen R, Zhou Z, Chen B, Kan H. Size-fractionated particle number concentrations and daily mortality in a Chinese city Environ Health Perspect. 2013 Oct;121(10):1174-8.

Zhao A, Chen R, Wang C, Zhao Z, Yang C. Associations between size-fractionated particulate air pollution and blood pressure in a panel of type II diabetes mellitus patients Environ Int. 2015 Jul;80:19-25.

Wang C, Chen R, Zhao Z, Cai J, Lu J. Particulate air pollution and circulating biomarkers among type 2 diabetic mellitus patients: the roles of particle size and time windows of exposure Environ Res. 2015 Jul;140:112-8.

Colais P, Serienelli M, Faustini A, Stafoggia M, Randi G. Air pollution and urgent hospital admissions in nine Italian cities. Results of the Epi Air Project Epidemiol Prev. 2009 Nov-Dec;33(6 Suppl 1):77-9.

Sen T, Astarcioglu MA, Asarcikli LD, Kilit C, Kafes H. The effects of air pollution and weather conditions on the incidence of acute myocardial infarction Am J Emerg Med. 2016 Mar;34(3):449-54.

Franchini M, Mannucci PM. Short-therm effects of air pollution on cardiovascular disease outcomes and mechanism. J Thromb Haemost. 2007;5:2169-74.