A rare manifestation of Ewing sarcoma: Primary intracranial Ewing sarcoma: Primary intracranial Ewing sarcoma

Eren Kıymaz; Ünal  Özüm

doi:10.28982/josam.8084

Authors

Eren Kıymaz Department of Neurosurgery, Sivas Cumhuriyet University Faculty of Medicine, Sivas, Turkey https://orcid.org/0000-0002-4868-6297
Ünal Özüm Department of Neurosurgery Sivas Cumhuriyet University Faculty of Medicine, Sivas, Turkey https://orcid.org/0000-0003-2065-2033

DOI:

https://doi.org/10.28982/josam.8084

Keywords:

Ewing sarcoma, primary intracranial Ewing sarcoma, dura invasion, muscle invasion, bone invasion

Abstract

Primary intracranial Ewing sarcoma (ES) is an extremely rare condition, frequently presenting as supratentorial and intraparenchymal. This case report presents a 22-year-old male diagnosed with primary intracranial ES exhibiting dura, muscle, and bone invasion. The patient initially presented with swelling in the preauricular region and was operated on with a preliminary diagnosis of meningioma, but pathology confirmed primary intracranial ES. This case highlights the rarity of primary intracranial ES and provides significant contributions to the diagnostic process.

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References

Lin PP, Wang Y, Lozano G. Mesenchymal Stem Cells and the Origin of Ewing’s Sarcoma. Sarcoma. 2011;2011:276463.

Applebaum MA, Worch J, Matthay KK, Goldsby R, Neuhaus J, West DC, et al. Clinical features and outcomes in patients with extraskeletal Ewing sarcoma. Cancer. 2011;117:3027-32.

Yu L, Craver R, Baliga M, et al. Isolated CNS involvement in Ewing’s sarcoma. Med Pediatr Oncol 1990;18:354-8.

Mendes WL, Osorio C, de Camargo B, Machado AB. Isolated CNS involvement in Ewing sarcoma. Med Pediatr Oncol. 1999;32:469-70.

Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, et al. The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol. 2021;23:1231-51.

Jaffe N. Advances in the management of malignant bone tumors in children and adolescents. Pediatr Clin N Am 1985;32:801-10.

Paulus W, Slowik F,Jellinger K. Primary intracranial sarcomas: Histopathological features of 19 cases. Histopathology 1991;18:395-402.

Chen J, Jiang Q, Zhang Y, Yu Y, Zheng Y, Chen J, et al. Clinical features and long-term outcome of primary intracranial Ewing sarcoma/peripheral primitive neuroectodermal tumors: 14 cases from a single in- stitution. World Neurosurg 2019;122:e1606-14.

Cherif El Asri A, Benzagmout M, Chakour K, Chaoui MF, Laaguili J, Chahdi H, et al. Primary intracranial pPNET/Ewing sarcoma: diagnosis, management, and prognostic factors dilemma–a systematic review of the literature. World Neurosurg 2018;115:346-56.

Jiang Y, Zhao L, Wang Y, Liu X, Wu X, Li Y. Primary Intracranial Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor Mimicking Meningioma: A Case Report and Literature Review. Front Oncol. 2020;6;10:528073.

Kim HJ, Kim JH, Park KJ, Park DH, Kang SH. Primary Intracranial Ewing Sarcoma With an Unusual Presentation: A Case Report. Brain Tumor Res Treat. 2024;12:115-20.

Jing Z, Wen-Yi L, Jian-Li L, Jun-Lin Z, Chi D. The imaging features of meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumours (pPNETS). Br J Radiol 2014;87:20130631.