Graded motor imagery in orthopedic and neurological rehabilitation: A systematic review of clinical studies

Graded motor imagery in rehabilitation

Authors

Keywords:

graded motor imagery, pain, chronic pain, motor imagery, rehabilitation

Abstract

Background/Aim: Graded motor imagery is an increasingly popular motion representation technique. However, treatment protocols for graded motor imagery vary depending on various diseases. This study aims to summarize the cases in which graded motor imagery therapy is used, study protocols, and outcome measures in studies.

Methods: The literature search was done with Web of Science, Pubmed, Scopus, and PEDro databases. The last search was carried out on September 13, 2022. A series-specific bias risk assessment tool was used with randomized, non-randomized, and case reports. All clinical studies that performed graded motor imagery, available in full text, describing their methods and findings, were included. The gender of the participants was not significant. The intervention was graded motor imagery. Outcome measures were mainly pain severity, other pain-related measures (e.g., pressure pain threshold, pain catastrophe), range of motion, strength, reaction time, kinesiophobia, neurophysiological measures, depression, function, or quality of life measures.

Results: Complex regional pain syndrome, distal radius fracture, phantom limb pain, stroke, cancer, pathological pain (phantom pain after amputation, pain after brachial plexus avulsion), elbow stiffness, frozen shoulder, chronic shoulder pain, and osteoarthritis conditions were included. The intervention duration in the studies varies from 2 to 8 weeks. A common outcome measure could not be determined among studies. The pain was assessed in 15 studies, although different rating scales were used. Graded motor imagery resulted in a reduction in pain in 14 of the 15 studies.

Conclusions: Due to the heterogeneity of the studies, a general conclusion regarding the effect of the disease-specific intervention was not possible. Based on pain outcome, graded motor imagery effectively decreased pain severity in various painful conditions.

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References

Moseley GL, Butler DS, Beames TB, Giles TJ. The graded motor imagery handbook: Noigroup publications; 2012.

Dilek B, Ayhan C, Yagci G, Yakut Y. Effectiveness of the graded motor imagery to improve hand function in patients with distal radius fracture: A randomized controlled trial. J Hand Ther. 2018;31(1):2-9. DOI: https://doi.org/10.1016/j.jht.2017.09.004

Shepherd M, Louw A, Podolak J. The clinical application of pain neuroscience, graded motor imagery, and graded activity with complex regional pain syndrome-A case report. Physiother Theory Pract. 2020;36(9):1043-55. DOI: https://doi.org/10.1080/09593985.2018.1548047

Moseley GL. Graded motor imagery for pathologic pain: a randomized controlled trial. Neurology. 2006;67(12):2129-34. DOI: https://doi.org/10.1212/01.wnl.0000249112.56935.32

Limakatso K, Corten L, Parker R. The effects of graded motor imagery and its components on phantom limb pain and disability in upper and lower limb amputees: A systematic review protocol. Systematic Reviews. 2016;5(1):145. DOI: https://doi.org/10.1186/s13643-016-0322-5

Moseley GL. Is successful rehabilitation of complex regional pain syndrome due to sustained attention to the affected limb? A randomised clinical trial. Pain. 2005;114(1-2):54-61. DOI: https://doi.org/10.1016/j.pain.2004.11.024

Moseley GL. Graded motor imagery is effective for long-standing complex regional pain syndrome: a randomised controlled trial. Pain. 2004;108(1-2):192-8. DOI: https://doi.org/10.1016/j.pain.2004.01.006

Lagueux E, Charest J, Lefrancois-Caron E, Mauger ME, Mercier E, Savard K, et al. Modified graded motor imagery for complex regional pain syndrome type 1 of the upper extremity in the acute phase: a patient series. Int J Rehabil Res. 2012;35(2):138-45. DOI: https://doi.org/10.1097/MRR.0b013e3283527d29

Strauss S, Barby S, Härtner J, Pfannmöller JP, Neumann N, Moseley GL, et al. Graded motor imagery modifies movement pain, cortical excitability and sensorimotor function in complex regional pain syndrome. Brain Commun. 2021;3(4):1-14. DOI: https://doi.org/10.1093/braincomms/fcab216

Strauss S, Barby S, Härtner J, Neumann N, Moseley GL, Lotze M. Modifications in fMRI Representation of Mental Rotation Following a 6 Week Graded Motor Imagery Training in Chronic CRPS Patients. J Pain. 2021;22(6):680-91. DOI: https://doi.org/10.1016/j.jpain.2020.12.003

Lagueux E, Bernier M, Bourgault P, Whittingstall K, Mercier C, Leonard G, et al. The Effectiveness of Transcranial Direct Current Stimulation as an Add-on Modality to Graded Motor Imagery for Treatment of Complex Regional Pain Syndrome: A Randomized Proof of Concept Study. Clin J Pain. 2018;34(2):145-54. DOI: https://doi.org/10.1097/AJP.0000000000000522

Walz AD, Usichenko T, Moseley GL, Lotze M. Graded motor imagery and the impact on pain processing in a case of CRPS. Clin J Pain. 2013;29(3):276-9. DOI: https://doi.org/10.1097/AJP.0b013e318250f4e8

Priganc VW, Stralka SW. Graded motor imagery. J Hand Ther. 2011;24(2):164-8. DOI: https://doi.org/10.1016/j.jht.2010.11.002

Limakatso K, Madden VJ, Manie S, Parker R. The effectiveness of graded motor imagery for reducing phantom limb pain in amputees: a randomised controlled trial. Physiotherapy. 2020;109:65-74. DOI: https://doi.org/10.1016/j.physio.2019.06.009

Araya-Quintanilla F, Gutierrez-Espinoza H, Jesus Munoz-Yanez M, Rubio-Oyarzun D, Cavero-Redondo I, Martinez-Vizcaino V, et al. The Short-term Effect of Graded Motor Imagery on the Affective Components of Pain in Subjects with Chronic Shoulder Pain Syndrome: Open-Label Single-Arm Prospective Study. Pain Med. 2020;21(10):2496-501. DOI: https://doi.org/10.1093/pm/pnz364

Casanova-Garcia C, Lara SL, Ruiz MP, Dominguez DR, Sosa ES. Non-pharmacological treatment for neuropathic pain in children with cancer. Med Hypotheses. 2015;85(6):791-7. DOI: https://doi.org/10.1016/j.mehy.2015.10.007

Gurudut P, Jaiswal R. Comparative Effect of Graded Motor Imagery and Progressive Muscle Relaxation on Mobility and Function in Patients with Knee Osteoarthritis: A Pilot Study. Altern Ther Health Med. 2022;28(3):42-7.

Sawyer EE, McDevitt AW, Louw A, Puentedura EJ, Mintken PE. Use of Pain Neuroscience Education, Tactile Discrimination, and Graded Motor Imagery in an Individual With Frozen Shoulder. J Orthop Sports Phys Ther. 2018;48(3):174-84. DOI: https://doi.org/10.2519/jospt.2018.7716

Polli A, Moseley GL, Gioia E, Beames T, Baba A, Agostini M, et al. Graded motor imagery for patients with stroke: a non-randomized controlled trial of a new approach. Eur J Phys Rehabil Med. 2017;53(1):14-23. DOI: https://doi.org/10.23736/S1973-9087.16.04215-5

Ji EK, Wang HH, Jung SJ, Lee KB, Kim JS, Jo L, et al. Graded motor imagery training as a home exercise program for upper limb motor function in patients with chronic stroke: A randomized controlled trial. Medicine. 2021;100(3):1-5. DOI: https://doi.org/10.1097/MD.0000000000024351

Birinci T, Kaya Mutlu E, Altun S. The efficacy of graded motor imagery in post-traumatic stiffness of elbow: a randomized controlled trial. J Shoulder Elbow Surg. 2022;31(10):2147-56. DOI: https://doi.org/10.1016/j.jse.2022.05.031

Bowering KJ, O'Connell NE, Tabor A, Catley MJ, Leake HB, Moseley GL, et al. The effects of graded motor imagery and its components on chronic pain: a systematic review and meta-analysis. J Pain. 2013;14(1):3-13. DOI: https://doi.org/10.1016/j.jpain.2012.09.007

Méndez-Rebolledo G, Gatica-Rojas V, Torres-Cueco R, Albornoz-Verdugo M, Guzmán-Muñoz E. Update on the effects of graded motor imagery and mirror therapy on complex regional pain syndrome type 1: A systematic review. J Back Musculoskelet Rehabil. 2017;30(3):441-9. DOI: https://doi.org/10.3233/BMR-150500

Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med. 2009;151(4):65-94. DOI: https://doi.org/10.7326/0003-4819-151-4-200908180-00136

Methley AM, Campbell S, Chew-Graham C, McNally R, Cheraghi-Sohi S. PICO, PICOS and SPIDER: a comparison study of specificity and sensitivity in three search tools for qualitative systematic reviews. BMC Health Serv Res. 2014 November 21;14:579. DOI: https://doi.org/10.1186/s12913-014-0579-0

Jovell AJ, Navarro-Rubio MD. [Evaluation of scientific evidence]. Medicina clinica. 1995;105(19):740-3.

Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al. Cochrane handbook for systematic reviews of interventions: John Wiley & Sons; 2019. DOI: https://doi.org/10.1002/9781119536604

Jüni P, Loke Y, Pigott T, Ramsay C, Regidor D, Rothstein H, et al. Risk of bias in non-randomized studies of interventions (ROBINS-I): detailed guidance. Br Med J. 2016.

Higgins J. Cochrane handbook for systematic reviews of interventions. Version 5.1. 0 [updated March 2011]. The Cochrane Collaboration. 2011.

Murad MH, Sultan S, Haffar S, Bazerbachi F. Methodological quality and synthesis of case series and case reports. BMJ Evid Based Med. 2018;23(2):60-3. DOI: https://doi.org/10.1136/bmjebm-2017-110853

Dudhani S, Anwar KAM, Jain PK. Can Brain Cure Pain and Fear? Effect of Graded Motor Imagery on Post Operative Lumbar Degenerative Diseases-Randomized Control Trial. Website: www ijpot com. 2020;14(1):244.

Johnson S, Hall J, Barnett S, Draper M, Derbyshire G, Haynes L, et al. Using graded motor imagery for complex regional pain syndrome in clinical practice: failure to improve pain. Eur J Pain. 2012;16(4):550-61. DOI: https://doi.org/10.1002/j.1532-2149.2011.00064.x

Louw A, Schmidt SG, Louw C, Puentedura EJ. Moving without moving: immediate management following lumbar spine surgery using a graded motor imagery approach: a case report. Physiother Theory Pract. 2015;31(7):509-17. DOI: https://doi.org/10.3109/09593985.2015.1060656

Quintal I, Poire-Hamel L, Bourbonnais D, Dyer JO. Management of long-term complex regional pain syndrome with allodynia: A case report. J Hand Ther. 2018;31(2):255-64. DOI: https://doi.org/10.1016/j.jht.2018.01.012

Anderson B, Meyster V. Treatment of a Patient With Central Pain Sensitization Using Graded Motor Imagery Principles: A Case Report. J Chiropr Med. 2018;17(4):264-7. DOI: https://doi.org/10.1016/j.jcm.2018.05.004

Gu P, Ye L, Li S. Regional homogeneity in patients with cerebral infarction and upper extremity hemiparesis before and after graded motor imagery training: a resting-state fMRI study. Chinese Journal of Rehabilitation Medicine. 2020;35(6):662-9.

Hall J, Mattheus C, McCabe CS. Graded Motor Imagery Programmes in Complex Regional Pain Syndrome: One Size Doesn't Fit All? Rheumatology. 2009;48:13-I4.

Lacuey-Barrachina E, Cuello-Ferrando A, Buil-Mur MI. Effectiveness of graduated motor imaging in complex regional pain syndrome-I. Cuestiones de Fisioterapia. 2020;49(1):55-64.

Ramella M, Borgnis F, Giacobbi G, Castagna A, Baglio F, Cortesi M, et al. Modified Graded Motor Imagery for Musicians' Focal Dystonia: A Case Series. Med Probl Perform Art. 2021;36(1):10-7. DOI: https://doi.org/10.21091/mppa.2021.1002

Lluch-Girbés E, Dueñas L, Mena-del Horno S, Luque-Suarez A, Navarro-Ledesma S, Louw A. A central nervous system-focused treatment approach for people with frozen shoulder: protocol for a randomized clinical trial. Trials. 2019;20(1):498. DOI: https://doi.org/10.1186/s13063-019-3585-z

Rierola-Fochs S, Varela-Vasquez LA, Merchan-Baeza JA, Minobes-Molina E. Development and Validation of a Graded Motor Imagery Intervention for Phantom Limb Pain in Patients with Amputations (GraMI Protocol): A Delphi Study. Int J Environ Res Public Health. 2021;18(22):12240. DOI: https://doi.org/10.3390/ijerph182212240

Spera P, Poniewierski P, Kostiukow A, Samborski W. The impact of physical activity on the functional state of a small patient with cancer. Pol Merkur Lekarski. 2020;48(283):39-41.

Wand BM, O'Connell NE, Di Pietro F, Bulsara M. Managing Chronic Nonspecific Low Back Pain With a Sensorimotor Retraining Approach: Exploratory Multiple-Baseline Study of 3 Participants. Phys Ther. 2011;91(4):535-46. DOI: https://doi.org/10.2522/ptj.20100150

Kumar SP, Kumar A, Shenoy K, D'Souza M, Kumar VK. Guided/Graded Motor Imagery for Cancer Pain: Exploring the Mind-Brain Inter-relationship. Indian J Palliat Care. 2013;19(2):125-6. DOI: https://doi.org/10.4103/0973-1075.116704

Lagueux E, Bourgault P, Tousignant-Laflamme Y. Effectiveness of transcranial Direct Current Stimulation (tDCS) and Graded Motor Imagery (GMI) on neuropathic pain of complex regional pain syndrome type I. Clin J Pain. 2015;16(4):S94-S. DOI: https://doi.org/10.1016/j.jpain.2015.01.395

Morales-Osorio MA, Mejía Mejía J. Graded motor imagery in the phantom limb syndrome with pain. Revista de la Sociedad Espanola del Dolor. 2012;19(4):209-16.

Birinci T, Mutlu EK, Altun S. Graded Motor Imagery in Posttraumatic Stiffness of the Elbow: A Pilot Study. Ann Rheum Dis. 2020;79:909-10. DOI: https://doi.org/10.1136/annrheumdis-2020-eular.2660

Gurudut P, Godse AN. Effectiveness of graded motor imagery in subjects with frozen shoulder: a pilot randomized controlled trial. Korean J Pain. 2022;35(2):152-9. DOI: https://doi.org/10.3344/kjp.2022.35.2.152

McGee C, Skye J, Van Heest A. Graded motor imagery for women at risk for developing type I CRPS following closed treatment of distal radius fractures: a randomized comparative effectiveness trial protocol. BMC Musculoskelet Disord. 2018;19(1):202. DOI: https://doi.org/10.1186/s12891-018-2115-6

Acerra NE, Souvlis T, Moseley GL. Stroke, complex regional pain syndrome and phantom limb pain: can commonalities direct future management? J Rehabil Med. 2007;39(2):109-14. DOI: https://doi.org/10.2340/16501977-0027

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Published

2023-05-01

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Review

How to Cite

1.
Candiri B, Talu B, Karabıcak GO. Graded motor imagery in orthopedic and neurological rehabilitation: A systematic review of clinical studies: Graded motor imagery in rehabilitation. J Surg Med [Internet]. 2023 May 1 [cited 2024 Dec. 3];7(5):347-54. Available from: https://jsurgmed.com/article/view/7669