Can hematologic inflammation markers be the indicator of early pregnancy loss?



Early pregnancy loss, Inflammation, Hematologic markers


Aim: Pregnancy loss occurs in 50% of human pregnancies and is the most common complication of early pregnancy. The aim of this study is to evaluate the relationship between early pregnancy loss and inflammation with hematological markers. Methods: This case-control study was carried out between January 2016-March 2019 in our clinic to evaluate the cases of early pregnancy loss. The early pregnancy loss group consisted of 94 patients, while the control group consisted of 104 women giving normal birth. Demographic data and complete blood count results of the groups were obtained from the patient files and hospital information management systems. Results: There were no statistically significant differences in terms of age and body mass index between the two groups. Pregnancy losses in the abortion group occurred at an average of 9.03 (3.62) weeks. In the abortus group, platelet count (P=0.003), NLR (P=0.036), PLR (P=0.032) and plateletcrit (P=0.007) were higher, while LMR (P=0.034) was lower, compared to the control group. Conclusions: Hematological inflammation parameters are easy to perform and cost-effective examinations. In our study, the success of these parameters to predict early pregnancy loss was evaluated, and it was found that although there are significant differences in hematological inflammation markers between the groups, the sensitivity and specificity of these markers are low.


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Research Article

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Onat T, Aydoğan Kırmızı D, Demir Çaltekin M, Başer E, Yalvaç ES. Can hematologic inflammation markers be the indicator of early pregnancy loss?. J Surg Med [Internet]. 2020 Nov. 1 [cited 2022 Dec. 7];4(11):952-5. Available from: