Obstructive sleep apnea syndrome (OSAS) related hypertension: A review of pathophysiology and potential therapeutic approaches

Ayşegül Navdar

doi:10.28982/josam.727915

Authors

Ayşegül Navdar https://orcid.org/0000-0002-0524-9791

DOI:

https://doi.org/10.28982/josam.727915

Keywords:

Obstructive Sleep Apnea Syndrome, Hypertension, CPAP, Upper airway surgery

Abstract

Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder related with cardiovascular diseases, including hypertension. There are lots of evidence supporting the relationship between OSAS and hypertension, modulated by multiple factors, but the exact mechanisms underlying this complex cause and effect relationship remain unclear. The alternating pattern of OSAS-related hypertension is closely related with target organ damage, especially in the heart and brain. In this review, the etiological factors, clinical types, probable pathophysiologic mechanisms, diagnostic methods, and current therapeutic approaches to OSAS-related hypertension is discussed in the light of current literature.

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