Predictive value of plateletcrit in the diagnosis of lower extremity deep vein thrombosis
Keywords:Venous thrombosis, Platelets, Blood cells, Blood vessels
Aim: Deep vein thrombosis (DVT) is a prevalent cause of mortality and morbidity mostly seen in the lower extremities. Early diagnosis is important in terms of the usability of mechanical thrombolysis methods. In this study, we aimed to investigate the diagnostic value of Plateletcrit (PCT) values in patients with suspected DVT.
Methods: Patients who were admitted to our clinic with suspected DVT between January 10, 2017-January 10, 2020 were included in this retrospective cohort study. As a result of their examination with a preliminary diagnosis of DVT, patients who were not diagnosed with DVT were recorded as Group 1, and those with DVT were recorded as Group 2. Univariate and multivariate logistic regression analyses were performed to reveal parameters supporting the diagnosis of DVT.
Results: A total of 139 patients were included in the study. The mean ages of patients in Group 1 (n=33) and Group 2 (n=106) were 45.7 (11.3) years and 53.9 (12.8) years, respectively. Age, body mass index (BMI) and trauma history rates were significantly higher in Group 2 (P values: P=0.019, P=0.038, P=0.015, respectively). The mean platelet volume (MPV), C-reactive protein (CRP), D-Dimer and PCT values were significantly higher in group 2 (P values; P =0.001, P=0.018, P<0.001, P<0.001, respectively). In the ROC analysis, the cut-off value for PCT was 0.1989 (AUC = 0.732, P<0.001, 70.8% sensitivity, 66.7% specificity)
Conclusion: In this study, we found that PCT value, which can be obtained easily and cheaply from routine blood parameters, may be a predictor in patients with suspected DVT.
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