Predicting survival in gastric cancer: A prospective cohort study with 102 patients
Keywords:Gastric cancer, Survival, Course of disease
Aim: Gastric cancer is one of the most aggressive tumors of the gastrointestinal tract. Course of disease can be different in every case. The aim of this study was to evaluate prognosis of gastric cancer patients and factors affecting survival.
Methods: Observational cohort study was planned. Primary gastric cancer patients enrolled into study. Patients with rare tumors were excluded. Patients were divided in 4 groups; Group 1: patients suitable for surgery and underwent surgical resection, Group 2: patients that were discovered unresectable during operation, Group 3: patients that were radiological inoperable, Group 4: patients who refused the surgery. We analyzed survival among groups, and evaluated effecting factors.
Results: 102 patients were included in the study. Sixty-six patients underwent surgical resection (group 1). Five patients were diagnosed as inoperable during surgery (group 2). Six-teen patients were determined as inoperable by radiologic evaluation (group 3). Fifteen patients (group 4) were evaluated as operable; however they refused surgery. No differences were detected among groups in comparison of gender with p of 0.250 (table 1). However, age distribution was different between groups with p of 0.043 because group 4 is formed by older patients with mean age of 71.0 (10.0). Survival analysis showed that patients in group 1 (14.0 (5.1) months) had better survival than other groups (P=0.011). Male patients showed better survival than female patients (14 (1.9) vs 6 (1.8) months, P=0.002).
Conclusion: Although course of gastric cancer differs in every patient, proper surgery at certain stages seems to be a feasible treatment option with acceptable survival rates.
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Copyright (c) 2019 Koray Koşmaz, Mustafa Taner Bostancı, Mehmet Ali Çaparlar, Fatih Başak, Abdullah Şişik, Süleyman Kalcan, Ali Ediz Kıvanç, Kemal Tekeşin, Gürhan Baş, Orhan Alimoğlu
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