A rare and incidental finding during colonoscopy: solitary polypoid ganglioneuroma: A case report

Authors

Keywords:

Endoscopy, Ganglioneuroma, Colon polyp, Polypoid ganglioneuroma

Abstract

Ganglioneuromas (GNs) are benign, slow growing and well differentiated neuroectodermal neoplasias. They are derived from developing neuronal cells of the sympathetic nervous system. They occur mostly in children and are located in the posterior mediastinum, retroperitoneum. We present a case of incidental solitary polypoid ganglioneuroma of the colon. A 70 year old woman underwent colonoscopy for colon cancer screening. She has no abdominal or intestinal symptoms. In hepatic flexure of the colon a spherical polypoid lesion that was 1.4 cm in diameter was detected endoscopically. Biopsy was taken from the polyp. The histopathology revealed a biphasic polypoid tumour with ganglion cells and schwannian stroma on hematoxylin and eosin stain. Final histopathological diagnosis was polypoid ganglioneuroma of the colon. Ganglioneuromatous polyposis and diffuse ganglioneuromatosis are associated with several systemic syndromes. Solitary GNs are generally asymptomatic. Treatment of GNs depends on their size, location, and clinical findings such as bleeding or obstruction. Prognosis is usually excellent. Polypectomy is curative for polypoid GN. However the patients with ganglioneuromatous polyposis and diffuse form may need colectomy.

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References

Fiori E, Pozzessere C, Lamazza A, Leone G, Borrini F, Schillaci A, Mingazzini P. Endoscopic treatment of ganglioneuroma of the colon associated with a lipoma: a case report. J Med Case Rep. 2012 Sep 14;6:304. doi: 10.1186/1752-1947-6-304.

Sayki Arslan M, Ekiz F, Yilmaz G, Coban S, Savas B, Ensari A, Ormeci N. Ganglioneuromatous polyposis of the colon in a patient with multiple adenomatous polyps. Turk J Gastroenterol. 2012;23(6):780-3.

Ofori E, Ona M, Ramai D, Huang T, Xiao P, Reddy M. Colonic Ganglioneuroma: A Rare Finding during Colorectal Cancer Screening. Case Rep Gastroenterol. 2017 Aug 8;11(2):434-439. doi: 10.1159/000477716. eCollection 2017 May-Aug.

Kumar S, Singh S, Chandna A. Organ Preservation in a Case of Retroperitoneal Ganglioneuroma: A Case Report and Review of Literature. Case Rep Surg. 2016;2016:6597374. doi: 10.1155/2016/6597374. Epub 2016 Sep 7.

Matthews MA, Adler BH, Arnold MA, Kumar S, Carvalho R, Besner GE. Diffuse intestinal ganglioneuromatosis in a child. J Pediatr Surg. 2013 May;48(5):1129-33. doi: 10.1016/j.jpedsurg.2013.03.066.

Abraham G, Prakash SR. Solitary Colonic Ganglioneuroma: A Rare Incidental Finding of Hematochezia. Case Rep Gastrointest Med. 2015;2015:794985. doi: 10.1155/2015/794985. Epub 2015 May 14.

Shekitka KM, Sobin LH. Ganglioneuromas of the gastrointestinal tract. Relation to Von Recklinghausen disease and other multiple tumor syndromes. Am J Surg Pathol. 1994 Mar;18(3):250-7.

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Published

2019-03-15

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Section

Case Report

How to Cite

1.
Usturalı Keskin E, Yılmaz T, Şen G. A rare and incidental finding during colonoscopy: solitary polypoid ganglioneuroma: A case report. J Surg Med [Internet]. 2019 Mar. 15 [cited 2024 Mar. 28];3(3):274-5. Available from: https://jsurgmed.com/article/view/502639