A case of parathyroid carcinoma mimicking parathyroid adenoma

Semra Demirli Atıcı; Değercan Yeşilyurt; Dudu Solakoğlu Kahraman; Emre Dikmeer; Hakan Öğücü; Halit Batuhan Demir; Gökhan Akbulut

doi:10.28982/josam.473603

Authors

Semra Demirli Atıcı https://orcid.org/0000-0002-8287-067X
Değercan Yeşilyurt https://orcid.org/0000-0001-6938-2076
Dudu Solakoğlu Kahraman https://orcid.org/0000-0002-4126-5326
Emre Dikmeer https://orcid.org/0000-0001-9442-0273
Hakan Öğücü https://orcid.org/0000-0003-4089-1162
Halit Batuhan Demir https://orcid.org/0000-0002-2746-7941
Gökhan Akbulut https://orcid.org/0000-0000-0002-1970

DOI:

https://doi.org/10.28982/josam.473603

Keywords:

Hypercalcemia, Primary hyperparathyroidism, Parathyroid adenoma, Parathyroid carcinoma

Abstract

Parathyroid carcinoma is one of the rare endocrine tumors and constitutes 1% of the cases with primary hyperparathyroidism. Because of similar imaging modalities and similar clinical findings, it is difficult to distinguish between preoperative parathyroid adenomas and parathyroid carcinoma. A 70-year-old female patient presented with fatigue and generalized bone pain. Her laboratory tests, neck and parathyroid scintigraphy were compatible with primary hyperparathyroidism with a significantly elevated level of parathormone. With the imaging methods which supported parathyroid adenoma, the patient was operated with a presumptive diagnosis of primary hyperparathyroidism due to parathyroid adenoma. The postoperative course was unremarkable and she was discharged on the postoperative fifth day. Postoperative pathology was reported as parathyroid carcinoma developed in a parathyroid adenoma. Parathyroid carcinoma and parathyroid adenoma have similar clinically and imaging methods, it is difficult to diagnose preoperatively.

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