Antimicrobial resistance pattern of Klebsiella spp isolated from patients in Tehran, Iran


  • Mohammad Mehdi Soltan Dallal
  • Mohammad Khalifeh-Gholi
  • Sara Sharifi Yazdi
  • Fariborz Mehrani
  • Azim Hadayatpour
  • Mohammad Kazem Sharifi Yazdi


Klebsiella, Infection, Antibiotic resistance


Aim: The majority of clinical specimens infected can be by Klebsiella species. Furthermore the incidence of drug resistant Klebsiella is increasing, therefore drug resistance sensitivity test it seems necessary before prescribing antibiotics. The aim of this research was to determine the pattern of antimicrobial resistance of Klebsiella species from clinical.

Methods: The present research was performed on 300 specimens of Klebsiella collected from hospitalized patients between 2016 and 2017. Identification was carried out according to standard procedure, and drug sensitivity test was determined by Kirby-Bauer method.

Results: The frequency rates of the isolated Klebsiella species were: pneumonia (94%), oxytoca (4%), ozaenae (1%), and rhinoscleromatis (1%). The collected samples in order of frequency were: urine, sputum, vagina, scar, stool, and blood respectively. The percentage rates of resistance were as follows: Ampicillin (97%), amoxycillin (97%), cephalothin (39%), gentamicin (30%), colistin (55%), nalidixic acid (2%), chloramphenicol (26%), kanamycin (17%), tetracycline (28%), nitrofurantoin (44%), ceftazidime (2%), and amikacin (0%).

Conclusion: The lowest resistance rate obtained with amikacin in all tested Klebsiella; which can be recommended as the most effective antibiotic.


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Soltan Dallal MM, Khalifeh-Gholi M, Sharifi Yazdi S, Mehrani F, Hadayatpour A, Sharifi Yazdi MK. Antimicrobial resistance pattern of Klebsiella spp isolated from patients in Tehran, Iran. J Surg Med [Internet]. 2018 May 1 [cited 2024 Apr. 14];2(2):84-6. Available from: