Yıl 2021, Cilt 5 , Sayı 1, Sayfalar 93 - 96 2021-01-01

Serum adropin and nitric oxide levels in missed abortus cases

Hacer PAŞAOĞLU [1] , Rulin DENİZ [2]


Background/Aim: Missed abortus is an emergency obstetric pathology, defined as intrauterine fetal viability loss before the 20th week of pregnancy. It is known that there is a correlation between endothelium dysfunction, neovascularization, hemodynamic regulation and adropin and nitric oxide levels. In this study, it is intended to research the possible roles of adropin and nitric levels in etiopathogenesis. Methods: In this case-control study, a total of fifty-nine volunteers, including healthy pregnant women and missed abortion cases, were included in the study. They were divided into 2 groups, as healthy individuals (Group 1, n=29), and those diagnosed with missed abortus (Group 2, n=30). Group 2 patients were followed weekly until β-HCG values fell below 5 ng/ml after termination. Serum adropin and nitric oxide levels were measured in all participants and those diagnosed with missed abortion when negative β-HCG value was obtained after termination. Results: Serum adropin and nitric oxide levels were significantly low in the missed abortus group (P=0.03) compared to healthy pregnant women, and in the missed abortus group compared to those whose β-HCG fell below 5 ng/ml after termination (P=0.02), while nitric oxide levels were similar in the latter comparison (P=0.38). Regarding age, body mass index, obstetric parameters, and other biochemical parameters, the two groups were similar (P>0.05 for each). Conclusion: This is the first research which evaluates adropin levels in missed abortus cases. Lower adropin and nitric oxide levels in missed abortus cases, and their increase after post-termination show that they may be playing a role in abortus etiopathogenesis.
Missed Abortus, Adropin, Nitrik Oxide
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Birincil Dil en
Konular Kadın Hastalıkları ve Doğum
Bölüm Araştırma makalesi
Yazarlar

Orcid: 0000-0003-1326-6441
Yazar: Hacer PAŞAOĞLU
Kurum: KADIN HASTALIKLARI VE DOĞUM ÖZEL MUAYENEHANESİ MERKEZ/KARS
Ülke: Turkey


Orcid: 0000-0002-7306-8212
Yazar: Rulin DENİZ (Sorumlu Yazar)
Kurum: KAFKAS ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, KADIN HASTALIKLARI VE DOĞUM ANABİLİM DALI
Ülke: Turkey


Destekleyen Kurum Bulunmamaktadır.
Teşekkür We’d like to thank Prof. Dr. Süleyman Aydın for evaluating the biochemical parameters and Assoc. Prof. Dr. Yakup Baykuş for his contributions about the planning of the study.
Tarihler

Yayımlanma Tarihi : 1 Ocak 2021

Bibtex @araştırma makalesi { josam867760, journal = {Journal of Surgery and Medicine}, issn = {}, eissn = {2602-2079}, address = {jsurgmed@gmail.com}, publisher = {Fatih BAŞAK}, year = {2021}, volume = {5}, pages = {93 - 96}, doi = {10.28982/josam.867760}, title = {Serum adropin and nitric oxide levels in missed abortus cases}, key = {cite}, author = {Paşaoğlu, Hacer and Deniz, Rulin} }
APA Paşaoğlu, H , Deniz, R . (2021). Serum adropin and nitric oxide levels in missed abortus cases . Journal of Surgery and Medicine , 5 (1) , 93-96 . DOI: 10.28982/josam.867760
MLA Paşaoğlu, H , Deniz, R . "Serum adropin and nitric oxide levels in missed abortus cases" . Journal of Surgery and Medicine 5 (2021 ): 93-96 <http://jsurgmed.com/tr/pub/issue/59430/867760>
Chicago Paşaoğlu, H , Deniz, R . "Serum adropin and nitric oxide levels in missed abortus cases". Journal of Surgery and Medicine 5 (2021 ): 93-96
RIS TY - JOUR T1 - Serum adropin and nitric oxide levels in missed abortus cases AU - Hacer Paşaoğlu , Rulin Deniz Y1 - 2021 PY - 2021 N1 - doi: 10.28982/josam.867760 DO - 10.28982/josam.867760 T2 - Journal of Surgery and Medicine JF - Journal JO - JOR SP - 93 EP - 96 VL - 5 IS - 1 SN - -2602-2079 M3 - doi: 10.28982/josam.867760 UR - https://doi.org/10.28982/josam.867760 Y2 - 2021 ER -
EndNote %0 Journal of Surgery and Medicine Serum adropin and nitric oxide levels in missed abortus cases %A Hacer Paşaoğlu , Rulin Deniz %T Serum adropin and nitric oxide levels in missed abortus cases %D 2021 %J Journal of Surgery and Medicine %P -2602-2079 %V 5 %N 1 %R doi: 10.28982/josam.867760 %U 10.28982/josam.867760
ISNAD Paşaoğlu, Hacer , Deniz, Rulin . "Serum adropin and nitric oxide levels in missed abortus cases". Journal of Surgery and Medicine 5 / 1 (Ocak 2021): 93-96 . https://doi.org/10.28982/josam.867760
AMA Paşaoğlu H , Deniz R . Serum adropin and nitric oxide levels in missed abortus cases. J Surg Med. 2021; 5(1): 93-96.
Vancouver Paşaoğlu H , Deniz R . Serum adropin and nitric oxide levels in missed abortus cases. Journal of Surgery and Medicine. 2021; 5(1): 93-96.
IEEE H. Paşaoğlu ve R. Deniz , "Serum adropin and nitric oxide levels in missed abortus cases", Journal of Surgery and Medicine, c. 5, sayı. 1, ss. 93-96, Oca. 2021, doi:10.28982/josam.867760