Year 2020, Volume 4 , Issue 11, Pages 1036 - 1040 2020-11-01

Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study
Sirozda sağ ventrikül disfonksiyonu: Speckle-tracking ekokardiyografi çalışması

Deniz OGUTMEN KOC [1] , Tayfun ŞAHİN [2] , Sila OKSUZ [3] , Hulya CEBE [4] , Ali Erkan DUMAN [5] , Yasemin GÖKDEN [6] , Ugur KORKMAZ [7] , Tanyeli GÜNEYLİGİL [8]


Aim: The majority of studies on cardiac dysfunction in patients with cirrhosis are associated with left ventricular (LV) myocardial dysfunction, with fewer studies on right ventricular (RV) function. The aims of this study were to evaluate biventricular function, particularly RV function, in patients with cirrhosis and investigate its relationship with disease severity. Methods: We included 50 hospitalized and ambulatory patients with cirrhosis and 33 healthy controls. Echocardiographic evaluation was performed with speckle-tracking analysis. Liver disease was graded according to Child-Pugh and Model for End-Stage Liver Disease (MELD) scores. Results: In our study, the most prevalent etiology of cirrhosis was viral hepatitis (60%), followed by non-alcoholic fatty liver disease (24%). RV-global longitudinal strain (GLS) and LV ejection fraction (EF) values were lower in patients with cirrhosis compared to the control group (both, P=0.001). LVEF was <55% in 19 (38%) patients. Decreases in RV-GLS and LVEF values were more common in patients with ascites (both, P=0.001). However, measurements of RV-GLS and LVEF did not distinguish the degree of severity of liver disease on the basis of Child-Pugh and MELD scores. LV-GLS values between patients with cirrhosis and the control group were similar (P=0.896). Conclusions: This study showed that RV function was impaired in patients with cirrhosis and more commonly, in patients with ascites. However, values of RV-GLS did not distinguish the degree of severity of liver disease. In addition, the LVEF was low and LV-GLS was normal in patients with cirrhosis.
Amaç: Sirozlu hastalarda kardiyak disfonksiyon üzerine yapılan çalışmaların çoğu, sol ventriküler (LV) miyokardiyal disfonksiyon ile ilişkilidir ve sağ ventrikül (RV) fonksiyonu üzerine daha az çalışma vardır. Bu çalışmanın amacı sirozlu hastalarda özellikle RV fonksiyonu olmak üzere, biventriküler fonksiyonu değerlendirmek ve hastalık şiddeti ile ilişkisini araştırmaktır. Yöntemler: Hastanede yatan ve ayakta tedavi gören 50 siroz hastası ve 33 sağlıklı kontrol çalışmamıza dahil edildi. Ekokardiyografik değerlendirme speckle-tracking analizi ile yapıldı. Karaciğer hastalığı Child-Pugh ve Son Evre Karaciğer Hastalığı Modeli (MELD) puanlarına göre derecelendirildi. Bulgular: Çalışmamızda sirozun en yaygın etiyolojisi viral hepatit (%60), ardından non-alkolik yağlı karaciğer hastalığı (%24) idi. Sirozlu hastalarda RV-global longitudinal strain (GLS) ve LV ejeksiyon fraksiyonu (EF) değerleri kontrol grubuna göre daha düşüktü (her ikisi de P=0.001). LVEF, 19 (% 38) hastada < %55 idi. Asitli hastalarda RV-GLS ve LVEF değerlerindeki düşüşler daha sıktı (her ikisi de, P=0,001). Bununla birlikte, RV-GLS ve LVEF ölçümleri, Child-Pugh ve MELD skorlarına göre karaciğer hastalığının şiddet derecesini ayırt etmedi. Sirozlu hastalar ile kontrol grubu arasındaki LV-GLS değerleri benzerdi (P=0.896). Sonuç: Bu çalışma, RV fonksiyonunun sirozlu hastalarda ve daha sık olarak asitli hastalarda bozulduğunu göstermiştir. Bununla birlikte, RV-GLS değerleri, karaciğer hastalığının şiddet derecesini ayırt etmedi. Ayrıca sirozlu hastalarda LVEF düşüktü ve LV-GLS normaldi.
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Primary Language en
Subjects Gastroenterology and Hepatology, Cardiac and Cardiovascular Systems
Journal Section Research article
Authors

Orcid: 0000-0003-2738-625X
Author: Deniz OGUTMEN KOC (Primary Author)
Institution: University of Health Sciences Gaziosmanpasa Training and Research Hospital, Department of Gastroenterology
Country: Turkey


Orcid: 0000-0002-0851-2946
Author: Tayfun ŞAHİN
Institution: Kocaeli University School of Medicine, Department of Cardiology
Country: Turkey


Orcid: 0000-0003-4721-0585
Author: Sila OKSUZ
Institution: University of Health Sciences Gaziosmanpasa Training and Research Hospital, Department of Internal Medicine
Country: Turkey


Orcid: 0000-0003-1954-406X
Author: Hulya CEBE
Institution: University of Health Sciences Gaziosmanpasa Training and Research Hospital, Department of Cardiology
Country: Turkey


Orcid: 0000-0002-7093-2503
Author: Ali Erkan DUMAN
Institution: Kocaeli University School of Medicine, Department of Gastroenterology
Country: Turkey


Orcid: 0000-0001-6767-3072
Author: Yasemin GÖKDEN
Institution: University of Health Sciences Cemil Tascıoglu City Hospital, Department of Gastroenterology
Country: Turkey


Orcid: 0000-0002-1103-5343
Author: Ugur KORKMAZ
Institution: Adatip Istanbul Hospital, Department of Gastroenterology
Country: Turkey


Orcid: 0000-0002-4191-1244
Author: Tanyeli GÜNEYLİGİL
Institution: Gaziantep University Faculty of Medicine, Department of Biostatistics
Country: Turkey


Dates

Publication Date : November 1, 2020

Bibtex @research article { josam818638, journal = {Journal of Surgery and Medicine}, issn = {}, eissn = {2602-2079}, address = {jsurgmed@gmail.com}, publisher = {Fatih BAŞAK}, year = {2020}, volume = {4}, pages = {1036 - 1040}, doi = {10.28982/josam.818638}, title = {Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study}, key = {cite}, author = {Ogutmen Koc, Deniz and Şahi̇n, Tayfun and Oksuz, Sila and Cebe, Hulya and Duman, Ali Erkan and Gökden, Yasemin and Korkmaz, Ugur and Güneyli̇gi̇l, Tanyeli} }
APA Ogutmen Koc, D , Şahi̇n, T , Oksuz, S , Cebe, H , Duman, A , Gökden, Y , Korkmaz, U , Güneyli̇gi̇l, T . (2020). Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study . Journal of Surgery and Medicine , 4 (11) , 1036-1040 . DOI: 10.28982/josam.818638
MLA Ogutmen Koc, D , Şahi̇n, T , Oksuz, S , Cebe, H , Duman, A , Gökden, Y , Korkmaz, U , Güneyli̇gi̇l, T . "Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study" . Journal of Surgery and Medicine 4 (2020 ): 1036-1040 <http://jsurgmed.com/en/pub/issue/57748/818638>
Chicago Ogutmen Koc, D , Şahi̇n, T , Oksuz, S , Cebe, H , Duman, A , Gökden, Y , Korkmaz, U , Güneyli̇gi̇l, T . "Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study". Journal of Surgery and Medicine 4 (2020 ): 1036-1040
RIS TY - JOUR T1 - Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study AU - Deniz Ogutmen Koc , Tayfun Şahi̇n , Sila Oksuz , Hulya Cebe , Ali Erkan Duman , Yasemin Gökden , Ugur Korkmaz , Tanyeli Güneyli̇gi̇l Y1 - 2020 PY - 2020 N1 - doi: 10.28982/josam.818638 DO - 10.28982/josam.818638 T2 - Journal of Surgery and Medicine JF - Journal JO - JOR SP - 1036 EP - 1040 VL - 4 IS - 11 SN - -2602-2079 M3 - doi: 10.28982/josam.818638 UR - https://doi.org/10.28982/josam.818638 Y2 - 2020 ER -
EndNote %0 Journal of Surgery and Medicine Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study %A Deniz Ogutmen Koc , Tayfun Şahi̇n , Sila Oksuz , Hulya Cebe , Ali Erkan Duman , Yasemin Gökden , Ugur Korkmaz , Tanyeli Güneyli̇gi̇l %T Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study %D 2020 %J Journal of Surgery and Medicine %P -2602-2079 %V 4 %N 11 %R doi: 10.28982/josam.818638 %U 10.28982/josam.818638
ISNAD Ogutmen Koc, Deniz , Şahi̇n, Tayfun , Oksuz, Sila , Cebe, Hulya , Duman, Ali Erkan , Gökden, Yasemin , Korkmaz, Ugur , Güneyli̇gi̇l, Tanyeli . "Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study". Journal of Surgery and Medicine 4 / 11 (November 2020): 1036-1040 . https://doi.org/10.28982/josam.818638
AMA Ogutmen Koc D , Şahi̇n T , Oksuz S , Cebe H , Duman A , Gökden Y , Korkmaz U , Güneyli̇gi̇l T . Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study. J Surg Med. 2020; 4(11): 1036-1040.
Vancouver Ogutmen Koc D , Şahi̇n T , Oksuz S , Cebe H , Duman A , Gökden Y , Korkmaz U , Güneyli̇gi̇l T . Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study. Journal of Surgery and Medicine. 2020; 4(11): 1036-1040.
IEEE D. Ogutmen Koc , T. Şahi̇n , S. Oksuz , H. Cebe , A. Duman , Y. Gökden , U. Korkmaz and T. Güneyli̇gi̇l , "Right ventricular dysfunction in cirrhosis: A speckle-tracking echocardiography study", Journal of Surgery and Medicine, vol. 4, no. 11, pp. 1036-1040, Nov. 2020, doi:10.28982/josam.818638