TY - JOUR AU - Yiğit Özay, Hülya AU - Turan, Sema PY - 2022/08/31 Y2 - 2024/03/29 TI - Experience with intraoperative extracorporeal membrane oxygenation in lung transplantation: intraoperative indicators: Extracorporeal membrane oxygenation in lung transplant JF - Journal of Surgery and Medicine JA - J Surg Med VL - 6 IS - 8 SE - Research Article DO - 10.28982/josam.7266 UR - https://jsurgmed.com/article/view/7266 SP - 718-722 AB - <p><strong>Background/Aim: </strong>Intraoperative extracorporeal membrane oxygenation (ECMO) is being used with increasing frequency in lung transplantation. However, the factors associated with the use of intraoperative ECMO in lung transplant patients are not yet conclusive. In this study, we aimed to determine the effective factors for providing intraoperative ECMO support in patients undergoing lung transplantation. In addition, we aimed to evaluate the effect of ECMO support on morbidity and mortality.</p><p><strong>Methods: </strong>In this retrospective cohort study evaluating lung transplant patients, patients were divided into two groups: those who received intraoperative ECMO support and those who did not. Demographic data, the lung allocation score (LAS) and pulmonary arterial pressure (PAP), intraoperative data, postoperative complications, duration of mechanical ventilation (MV), length of stay (LOS) in intensive care and hospital, and mortality rates were recorded for both groups. Factors affecting entry to ECMO were analyzed by Multivariate Logistic Regression.</p><p><strong>Results: </strong>In this period, 51.9% of 87 patients who underwent lung transplantation required intraoperative ECMO. The mean age, LAS, and PAP of the ECMO group were significantly higher than the non-ECMO group (<em>P = </em>0.043, <em>P = </em>0.007, and <em>P = </em>0.007, respectively). In multivariate analysis, it was found that lower MAP averages were a predictive parameter in intraoperative ECMO requirements (OR: 1.091; CI: 1.009-1.179; <em>P = </em>0.028). The ECMO group’s mechanical ventilation time and hospital mortality were significantly higher than the other group (<em>P = </em>0.004 and <em>P = </em>0.025, respectively).</p><p><strong>Conclusion: </strong>Preoperative indicators of intraoperative ECMO support were determined as age, LAS, and PAP elevation. In addition, low MAP levels and high lactate levels were always determined as intraoperative indicators in lung transplantation until the transition to ECMO support.</p> ER -