B-Mode ultrasound assessment of intima-media thickness of common carotid, internal carotid, brachial, femoral arteries and abdominal aorta in patients with cardiovascular risk factor

Authors

  • Ayşe Selcan Koç
  • Burçak Çakır Peköz

Keywords:

Intima-media thickness, Common carotid artery, Femoral artery

Abstract

Aim: The aim of the present study was to assess the association between common carotid intima-media thickness (IMT) and vascular IMT values measured from different anatomic regions.

Methods: We prospectively included 256 patients. The IMT values of the common carotid and internal carotid, brachial and femoral artery and abdominal aorta were measured by B-mode ultrasound (CC-IMT, IC-IMT, B-IMT, F-IMT and A-IMT). Patients were divided into two groups as increased and normal CC-IMT. 

Results: Increased CC-IMT was detected in 55 of 256 patients (21.5%). All IMT variables showed a positive correlation with CC-IMT. Femoral IMT was independently associated with increased CC-IMT. In regression model, each 0.1 mm increase in F-IMT increased the risk of increased CC-IMT by 70.2%. When F-IMT value 1.1 mm was accepted as a cut-off value for the prediction of increased CC-IMT, sensitivity and specificity were 96.4% and 90%, respectively. In ROC curve analyses, the area under curve was calculated as 0.936. 

Conclusions: Another vascular IMT location presenting increased CC-IMT best is F-IMT. The limit value for increased F-IMT >1.1mm may be used in practice. The CC-IMT measurement is closely and positively associated with all other vascular IMT measurements.

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References

Mancia G, Fagard R, Narkiewicz K, Redon J, Zanchetti A, Böhm M, et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J. 2013 Jul;34(28):2159-219.

Belhassen L, Carville C, Pelle G, Monin JL, Teiger E, Duval-Moulin AM, et al. Evaluation of carotid artery and aortic intima-media thickness measurements for exclusion of significant coronary atherosclerosis in patients scheduled for heart valve surgery. J Am Coll Cardiol. 2002;39:1139-44.

Handa N, Matsumoto M, Maeda H, Hougaku H, Ogawa S, Fukunaga R, et al. Ultrasonic evaluation of early carotid atherosclerosis. Stroke. 1990;21:1567–72.

Heiss G, Sharrett AR, Barnes R, Chambless LE, Szklo M, Alzola C. Carotid atherosclerosis measured by B-mode ultrasound in populations: associations with cardiovascular risk factors in the ARIC study. Am J Epidemiol. 1991;134:250–6.

Wofford JL, Kahl FR, Howard GR, McKinney WM, Toole JF, Crouse JR 3rd. Relation of extent of extracranial carotid artery atherosclerosis as measured by B-mode ultrasound to the extent of coronary atherosclerosis. Arterioscler Thromb. 1991;11:1786–94.

O’Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK, Jr., the Cardiovascular Health Study Collaborative Research Group. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. N Engl J Med. 1999;340:14–22.

Sartorato P, Zulian E, Benedini S, Mariniello B, Schiavi F, Bilora F, et al. Cardiovascular risk factors and ultrasound evaluation of intima-media thickness at common carotids, carotid bulbs, and femoral and abdominal aorta arteries in patients with classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency. J Clin Endocrinol Metab. 2007;92:1015-8.

Belhassen L, Carville C, Pelle G, Monin JL, Teiger E, Duval-Moulin AM, et al. Evaluation of carotid artery and aortic intima-media thickness measurements for exclusion of significant coronary atherosclerosis in patients scheduled for heart valve surgery. J Am Coll Cardiol. 2002;39:1139-44.

Kallizaros JE, Tsioufis CP, Stefanadis CI, Pitsavos CE, Toutouzas PK. Close relation between carotid and ascending aortic atherosclerosis in cardiac patients. Circulation. 2000;102:263–8.

Tomochika Y, Tanaka N, Ono S, Murata K, Muro A, Yamamura T, et al. Assessment by transesophageal echography of atherosclerosis of the descending thoracic aorta in patients with hypercholesterolemia. Am J Cardiol. 1999;83:703–9.

Labropoulos N, Zarge J, Mansour MA, Kang SS, Baker WH. Compensatory arterial enlargement is a common pathobiologic response in early atherosclerosis. Am J Surg. 1998;176:140–3.

Meena D, Prakash M, Gupta Y, Bhadada SK, Khandelwal N. Carotid, aorta and renal arteries intima-media thickness in patients with sporadic idiopathic hypoparathyroidism. Indian J Endocrinol Metab. 2015;19:262-6.

Neiva Neto EC, Piatto MJ, Paschôa AF, Godoy Ide B, Schlaad SW, Van Bellen B. Intima-media thickness: correlation between carotids, vertebral artery, aorta and femoral arteries. Int Angiol. 2015;34:269-75.

Lisowska A, Musiał WJ, Knapp M, Prokop J, Dobrzycki S. Carotid and femoral atherosclerotic lesions in patients with coronary heart disease confirmed by angiography. Kardiol Pol. 2005;63:636-42.

Iwamoto Y, Maruhashi T, Fujii Y, Idei N, Fujimura N, Mikami S, et al. Intima-media thickness of brachial artery, vascular function, and cardiovascular risk factors. Arterioscler Thromb Vasc Biol. 2012;32:2295-303.

Cheng KS, Mikhailidis DP, Hamilton G, Seifalian AM. A review of the carotid and femoral intima-media thickness as an indicator of the presence of peripheral vascular disease and cardiovascular risk factors. Cardiovasc Res. 2002;54:528-38.

Kirhmajer MV, Banfic L, Vojkovic M, Strozzi M, Bulum J, Miovski Z. Correlation of femoral intima-media thickness and the severity of coronary artery disease. Angiology. 2011;62:134-9.

Sorensen KE, Kristensen IB, Celermajer DS. Atherosclerosis in the human brachial artery. J Am Coll Cardiol. 1997;29:318-22.

Hafner F, Kieninger A, Meinitzer A, Gary T, Froehlich H, Haas E, et al. Endothelial dysfunction and brachial intima-media thickness: long term cardiovascular risk with claudication related to peripheral arterial disease: a prospective analysis. PLoS One. 2014;9:e93357.

Agewall S, Henareh L, Jogestrand T. Intima-media complex of both the brachial artery and the common carotid artery are associated with left ventricular hypertrophy in patients with previous myocardial infarction. J Hypertens. 2005;23:119-25.

Koyoshi R, Miura S, Kumagai N, Shiga Y, Mitsutake R, Saku K. Clinical significance of flow-mediated dilation, brachial intima-media thickness and pulse wave velocity in patients with and without coronary artery disease. Circ J. 2012;76:1469-75.

Kirhmajer MV, Banfic L, Vojkovic M, Strozzi M, Bulum J, Miovski Z. Correlation of femoral intima-media thickness and the severity of coronary artery disease. Angiology. 2011;62:134-9.

Lucatelli P, Fagnani C, Tarnoki AD, Tarnoki DL, Stazi MA, Salemi M, et al. Femoral Artery Ultrasound Examination. Angiology. 2017;68:257-65.

Depairon M, Tutta P, van Melle G, Hayoz D, Kappenberger L, Darioli R. Reference values of intima-medial thickness of carotid and femoral arteries in subjects aged 20 to 60 years and without cardiovascular risk factors. Arch Mal Coeur Vaiss. 2000;93:721-6.

Cheng KS, Mikhailidis DP, Hamilton G, Seifalian AM. A review of the carotid and femoral intima-media thickness as an indicator of the presence of peripheral vascular disease and cardiovascular risk factors. Cardiovasc Res. 2002;54:528-38.

Mita T, Katakami N, Shiraiwa T, Yoshii H, Gosho M, Shimomura I, et al. Dose-Dependent Effect of Sitagliptin on Carotid Atherosclerosis in Patients with Type 2 Diabetes Mellitus Receiving Insulin Treatment: A Post Hoc Analysis. Diabetes Ther. 2017;8:1135-46.

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Published

2018-09-01

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Section

Research Article

How to Cite

1.
Koç AS, Peköz B Çakır. B-Mode ultrasound assessment of intima-media thickness of common carotid, internal carotid, brachial, femoral arteries and abdominal aorta in patients with cardiovascular risk factor. J Surg Med [Internet]. 2018 Sep. 1 [cited 2024 Apr. 20];2(3):244-8. Available from: https://jsurgmed.com/article/view/421768